SNP information rs3212227

Research and publications:

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16600026   Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway

  16759385   Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  17236132   A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17587057   Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

  17901940   Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction.

  18045485   The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

  18219280   Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.

  18369459   A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.

  18383521   IL23R and IL12B polymorphisms in Spanish IBD patients: no evidence of interaction.

  18609743   Genetics of psoriasis and psoriatic arthritis: update and future direction.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18800148   Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis.

  19035472   Investigation of association of the IL12B and IL23R genes with psoriatic arthritis.

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19118071   Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women.

  19182814   New insights into the pathogenesis and genetics of psoriatic arthritis.

  19230157   Immunogenetics of seasonal influenza vaccine response.

  19235914   Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease.

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19705136   Genetic evidence for involvement of the IL23 pathway in Thai psoriatics.

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  19956101   Overview of the Rapid Response data

  19956104   Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium.

  19956106   Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

  19956109   Type I Diabetes Genetics Consortium Rapid Response Family-Based Candidate Gene Study: Strategy, Gene Selection, and Key Findings.

  20350312   Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya.

  20387064   Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults.

  20521253   IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population.

  20525402   Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study

  20544370   Association of genetic polymorphisms in the IL12-IFNG pathway with susceptibility to and prognosis of pulmonary tuberculosis in a Chinese population.

  20606885   Genetics of psoriasis and psoriatic arthritis.

  20711808   Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists

  20716621   Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.

  20811626   Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

  20818961   Inflammatory mediators gene polymorphisms in preeclampsia.

  20953186   Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.

  21198744   The clinical presentation of autoimmune thyroid disease in men is associated with IL12B genotype.

  21339808   Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina.

  21513752   Association of single nucleotide polymorphisms in interleukin 12 (IL-12A and -B) with asthma in a Chinese population.

  21658613   Host genetics in follicular lymphoma.

  21760883   Genetic determinants of UV-susceptibility in non-melanoma skin cancer.

  21875636   Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination.

  22045842   Association of IL-12B genetic polymorphism with the susceptibility and disease severity of ankylosing spondylitis.

  22046141   Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.

  22059093   Risk Factors of Non-Hodgkin Lymphoma.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22144535   Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.

  22170493   Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL.

  22241978   Vaccinomics and personalized vaccinology: is science leading us toward a new path of directed vaccine development and discovery?

  22372709   Cytokine gene polymorphisms in the susceptibility to acute coronary syndrome.

  22479607   Analysis of IL12B gene variants in inflammatory bowel disease.

  22515181   Interleukin-12: clinical usage and molecular markers of cancer susceptibility.

  22581790   Effect of IL12A and IL12B polymorphisms on the risk of Chlamydia trachomatis-induced tubal factor infertility and disease severity.

  22614250   Contribution of IL12A and IL12B polymorphisms to the risk of cervical cancer.

  22702905   Single nucleotide polymorphism in the interleukin 12B gene is associated with risk for breast cancer development.

  22734699   Association between single-nucleotide polymorphisms in interleukin-12A and risk of chronic obstructive pulmonary disease.

  22739501   Resequencing of the IL12B gene in psoriasis patients with the rs6887695/rs3212227 risk genotypes.

  22740240   Associations between polymorphisms in IL-12A, IL-12B, IL-12Rβ1, IL-27 gene and serum levels of IL-12p40, IL-27p28 with esophageal cancer.

  22754588   Risk Factors of Follicular Lymphoma.

  22788685   Polymorphisms of pro-inflammatory cytokine genes and the risk for acute suppurative or chronic nonsuppurative apical periodontitis in a Colombian population.

  22863216   Antibodies to hepatitis B virus surface antigen and interleukin 12 and interleukin 18 gene polymorphisms in hemodialysis patients.

  22897389   Interactions between adiposity and genetic polymorphisms on the risk of psoriasis.

  22940148   Functional polymorphisms in the interleukin-12 gene contribute to cancer risk: evidence from a meta-analysis of 18 case-control studies.

  22947458   Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso.

  23029430   Prognostic role of host cyclooxygenase and cytokine genotypes in a Caucasian cohort of patients with gastric adenocarcinoma.

  23065198   Interleukin-12B rs3212227 polymorphism and cancer risk: a meta-analysis.

  23065210   Interactions of interleukin-12A and interleukin-12B polymorphisms on the risk of intracranial aneurysm.

  23071570   Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level.

  23280621   Nucleotide variation in IL-10 and IL-12 and their receptors and cervical and vulvar cancer risk: a hybrid case-parent triad and case-control study.

  23297015   Meta-analysis of IL12B polymorphisms (rs3212227, rs6887695) with psoriasis and psoriatic arthritis.

  23406059   Inflammatory factors gene polymorphism in recurrent oral ulceration.

  23554684   Genetic susceptibility of cervical cancer.

  23578145   Levels of interleukin-(IL)-12p40 are markedly increased in Brucellosis among patients with specific IL-12B genotypes.

  23600862   Interleukin-12B gene polymorphism frequencies in Egyptians and sex-related susceptibility to hepatitis C infection.

  23886662   A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

  23922006   PharmGKB summary: cyclosporine and tacrolimus pathways.

  23955419   IL12B and IL23R gene SNPs in Japanese psoriasis.

  23991654   Association of interleukin-12 polymorphisms and serum IL-12p40 levels with osteosarcoma risk.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24158609   Association of the interleukin-12 polymorphic variants with the development of antibodies to surface antigen of hepatitis B virus in hemodialysis patients in response to vaccination or infection.

  24175098   The role of 39 psoriasis risk variants on age of psoriasis onset.

  24529168   Interleukin 12B rs3212227 T > G polymorphism was associated with an increased risk of gastric cardiac adenocarcinoma in a Chinese population.

  24547735   Association of IL-23 and its receptor gene single-nucleotide polymorphisms with multiple sclerosis in Chinese southern population.

  24859272   Genetic variations of IL-12B, IL-12Rβ1, IL-12Rβ2 in Behçet's disease and VKH syndrome.

  24957500   Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus.

  24971308   Genetic variations of cytokines and cytokine receptors in psoriasis patients from china.

  25037175   Association of IL-12A and IL-12B polymorphisms with susceptibility to Alzheimer's disease in a Han population.

  25075970   The associations between immunity-related genes and breast cancer prognosis in Korean women.

  25133031   Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature.

  25238536   Association of cytokines in individuals sensitive and insensitive to dust mites in a Brazilian population.

  25294155   A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

  25359546   Pro- and anti-inflammatory cytokine gene single-nucleotide polymorphisms in inflammatory bowel disease.

  25469587   Interaction of TLR-IFN and HLA polymorphisms on susceptibility of chronic HBV infection in Southwest Han Chinese.

  25469793   Association of polymorphisms in interleukin (IL)-12A and -B genes with rheumatoid arthritis in a Chinese population.

  25587543   T-cell cytokine gene polymorphisms and vitamin D pathway gene polymorphisms in end-stage renal disease due to type 2 diabetes mellitus nephropathy: comparisons with health status and other main causes of end-stage renal disease.

  25589894   High producing tumor necrosis factor alpha gene alleles in protection against severe manifestations of dengue.

  25928231   Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis.