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SNP information rs2494732

RS2494732

Normal allele: CC

The AKT1 genotype affects the risk of developing psychosis in cannabis users. It also increases the risk of schizophrenia in people with a break in this gene.

Polymorphism rs2494732 is related to topics like this:


Research and publications:

  16260726   Detection of functional single-nucleotide polymorphisms that affect apoptosis.

  16395129   Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.

  17464696   AKT1 and neurocognition in schizophrenia.

  18497887   Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans.

  18715757   Genetic associations with schizophrenia: meta-analyses of 12 candidate genes

  18855532   Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia.

  19051289   Association of AKT1 with verbal learning, verbal memory, and regional cortical gray matter density in twins.

  19461960   Absence of AKT1 mutations in glioblastoma.

  19931325   No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.

  20046382   AKT1 Gene Polymorphisms and Obstetric Complications in the Patients with Schizophrenia.

  21041608   Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up.

  21061022   AKT1 polymorphisms are associated with risk for metabolic syndrome.

  21728034   Methamphetamine-associated psychosis.

  21775978   AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder.

  21842521   AKT1 polymorphisms and survival of early stage non-small cell lung cancer.

  22150081   The AKT1 gene is associated with attention and brain morphology in schizophrenia.

  22277669   Genetic overlap between schizophrenia and bipolar disorder: a study with AKT1 gene variants and clinical phenotypes.

  22831980   Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users.

  23747160   No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.

  24077347   Associations between single-nucleotide polymorphisms in the PI3K-PTEN-AKT-mTOR pathway and increased risk of brain metastasis in patients with non-small cell lung cancer.

  24632578   Combined effects of genetic variants of the PTEN, AKT1, MDM2 and p53 genes on the risk of nasopharyngeal carcinoma.

  24803581   SNPs in PI3K-PTEN-mTOR and brain metastases in NSCLC--response.

  24860514   Gene-environment interactions in severe mental illness.

  24904437   Gone to Pot - A Review of the Association between Cannabis and Psychosis.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25060489   Genetic variants in AKT1 gene were associated with risk and survival of OSCC in Chinese Han Population.

  25184405   Subclinical psychotic experiences in healthy young adults: associations with stress and genetic predisposition.

  26683100   Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population.

  26694375   Alterations of Dopamine D2 Receptors and Related Receptor-Interacting Proteins in Schizophrenia: The Pivotal Position of Dopamine Supersensitivity Psychosis in Treatment-Resistant Schizophrenia.

  26828791   Polymorphisms in the AKT1 and AKT2 genes and oesophageal squamous cell carcinoma risk in an Eastern Chinese population.

  26882038   AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers.

  26988277   Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients.

  27018053   Progression and metastasis of lung cancer.

  27187382   Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects.

  27305091   Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia.

  27353512   Association of AKT1 gene polymorphisms with sporadic Parkinson's disease in the Chinese Han population.

  27554198   Cannabis and a lower BMI in psychosis: What is the role of AKT1?

  27876891   Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy.

  28363000   Association between single nucleotide polymorphisms in AKT1 and the risk of prostate cancer in the Chinese Han population.

  28822116   Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

  28900113   Abnormalities of signal transduction networks in chronic schizophrenia.

  29653893   Interaction between childhood adversity and functional polymorphisms in the dopamine pathway on first-episode psychosis.

  29867928   Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals.

  30065942   Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30781715   Genetic Epidemiology of Breast Cancer in Latin America.

  30976664   Phosphorylated-Akt overexpression is associated with a higher risk of brain metastasis in patients with non-small cell lung cancer.

  31445421   Trend level gene-gender interaction effect for the BDNF rs6265 variant on age of onset of psychosis.

  32319007   Effects of the mTOR and AKT genes polymorphisms on systemic lupus erythematosus risk.

  32398646   Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?

  32536252   The effect of the AKT1 gene and cannabis use on cognitive performance in healthy subjects.

  32590727   Combined effects of AKT serine/threonine kinase 1 polymorphisms and environment on congenital heart disease risk: A case-control study.

  33107190   Effects of the MTOR and AKT1 genes polymorphisms on papillary thyroid cancer development.

  33112820   Akt1 genetic variants confer increased susceptibility to thyroid cancer.

  34150619   Association of Inflammation-Related Gene Polymorphisms With Susceptibility and Radiotherapy Sensitivity in Head and Neck Squamous Cell Carcinoma Patients in Northeast China.

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