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SNP information rs2420946

RS2420946

Normal allele: CC

Polymorphism rs2420946 is related to topics like this:

BRCA gene

BRCA stands for "BReast CAncer gene" and refers to two distinct genes, BRCA1 and BRCA2, which have...


Research and publications:

  17529973   A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

  18285324   Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

  18326623   Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

  18483326   FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.

  18845558   Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women.

  19223389   FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.

  19497954   Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.

  19500394   Genetic variants of the FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.

  19582883   FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: results of a case control study in Japan.

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19789366   Evaluation of 11 breast cancer susceptibility loci in African-American women.

  19861516   Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer.

  20056625   Variation in the FGFR2 gene and the effect of a low-fat dietary pattern on invasive breast cancer.

  20300826   Current evidence on the relationship between three polymorphisms in the FGFR2 gene and breast cancer risk: a meta-analysis.

  20364400   Quantitative assessment of the effect of FGFR2 gene polymorphism on the risk of breast cancer.

  20554749   FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

  20560208   Powerful SNP-set analysis for case-control genome-wide association studies.

  20853316   FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.

  20959865   Genome-wide association of breast cancer: composite likelihood with imputed genotypes.

  21445572   Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

  21475998   Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States.

  21610108   A multistage association study identifies a breast cancer genetic locus at NCOA7.

  21655367   In search of breast cancer culprits: suspecting the suspected and the unsuspected.

  21695280   Pathways of distinction analysis: a new technique for multi-SNP analysis of GWAS data.

  21702935   Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.

  21853025   A bayesian method for evaluating and discovering disease loci associations.

  21869864   An integrative genomics approach to biomarker discovery in breast cancer.

  22212363   A robust method for testing association in genome-wide association studies.

  22303333   Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans.

  22332084   Research advances at the Institute for Nutritional Sciences at Shanghai, China.

  22734045   Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.

  22806168   A multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24.

  23184080   Assessing interactions between the associations of fibroblast growth factor receptor 2 common genetic variants and hormone receptor status with breast cancer risk.

  23221726   Gene-environment interactions for breast cancer risk among Chinese women: a report from the Shanghai Breast Cancer Genetics Study.

  23225170   Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population.

  23354978   Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.

  23519603   Variable selection and estimation in generalized linear models with the seamless L(0) penalty.

  23717390   Identification of a breast cancer susceptibility locus at 4q31.22 using a genome-wide association study paradigm.

  24054997   Association between rs2981582 polymorphism in the FGFR2 gene and the risk of breast cancer in Mexican women.

  24218030   Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach.

  24266904   Breast cancer prediction using genome wide single nucleotide polymorphism data.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24454457   Case-control study on the fibroblast growth factor receptor 2 gene polymorphisms associated with breast cancer in chinese han women.

  25285046   Graphical-model Based Multiple Testing under Dependence, with Applications to Genome-wide Association Studies.

  25404989   Learning Heterogeneous Hidden Markov Random Fields.

  25677745   Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.

  25788325   Evaluation of a two-stage framework for prediction using big genomic data.

  26421298   Heterogeneity of Breast Cancer Associations with Common Genetic Variants in FGFR2 according to the Intrinsic Subtypes in Southern Han Chinese Women.

  26728143   Variants of FGFR2 and their associations with breast cancer risk: a HUGE systematic review and meta-analysis.

  27708667   Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.

  28098224   Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

  28985766   Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations.

  29104507   Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.

  29872343   Association of FGFR2 and PI3KCA genetic variants with the risk of breast cancer in a Chinese population.

  29965997   Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.

  30359238   Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients.

  30781715   Genetic Epidemiology of Breast Cancer in Latin America.

  31113874   The association of genetic variants in FGFR2 with osteoporosis susceptibility in Chinese Han population.

  31142340   FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors - implications for therapy of luminal breast cancer.

  31178825   Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy.

  32287273   DOT: Gene-set analysis by combining decorrelated association statistics.

  32894086   MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population.

  33081025   The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives.

  33907591   A BAYESIAN GRAPHICAL MODEL FOR GENOME-WIDE ASSOCIATION STUDIES (GWAS).

  34359697   A Personal Breast Cancer Risk Stratification Model Using Common Variants and Environmental Risk Factors in Japanese Females.

  34514747   Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy.

  34759736   Fibroblast growth factor receptor 2 gene (FGFR2) rs2981582T/C polymorphism and susceptibility to breast cancer in Saudi women.

  35395775   Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women.

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