Normal allele: AA
Growing role of TRIB3 as a gene affecting human insulin resistance on glucose homeostasis by altering the interaction between insulin sensitivity and secretion.
Polymorphism rs2295490 is related to topics like this:
Research and publications:
18984671 The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.
23073174 From genotype to human β cell phenotype and beyond
23633196 Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.
26253791 Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes.
31231424 Genetic and Epigenetic Studies in Diabetic Kidney Disease.