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SNP information rs2236857

RS2236857

Normal allele: TT

The OPRD1 gene polymorphism is associated with opioid dependence.

Polymorphism rs2236857 is related to topics like this:

Is drug abuse genetic

There is a significant interest among individuals, particularly those with a familial background of...

Research and publications:

  16882734   Genetic predictors for acute experimental cold and heat pain sensitivity in humans

  17622222   The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk.

  18213616   Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations.

  18518925   Genetic susceptibility to heroin addiction: a candidate gene association study.

  19500151   Heroin addiction in African Americans: a hypothesis-driven association study.

  22020140   Molecular mechanisms of opioid receptor-dependent signaling and behavior.

  22074755   Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study.

  22500942   Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.

  22547174   The genetics of the opioid system and specific drug addictions.

  28035534   OPRD1 Genetic Variation and Human Disease.

  28632076   Association of OPRD1 Gene Variants with Opioid Dependence in Addicted Male Individuals Undergoing Methadone Treatment in the North of Iran.

  28692418   Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese.

  28976288   The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment.

  30171993   OPRD1 gene affects disease vulnerability and environmental stress in patients with heroin dependence in Han Chinese.

  34031368   OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics.

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