SNP information rs17817449

Research and publications:

  17928949   FTO polymorphisms in oceanic populations

  18218107   FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs

  18256137   Regulation of Fto/Ftm gene expression in mice and humans

  18316358   Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

  18487448   Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population

  18551112   Replication of genetic effects of FTO polymorphisms on BMI in a Korean population.

  18599522   FTO variants are associated with obesity in the Chinese and Malay populations in Singapore

  18647953   Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test

  18719664   The FTO gene is associated with adulthood obesity in the Mexican population

  18833210   The FTO gene and obesity in a large Eastern European population sample: the HAPIEE study.

  19265514   FTO gene variation and measures of body mass in an African population

  19278366   A common variant in the FTO gene is associated with body mass index in males and postmenopausal females but not in premenopausal females. Czech post-MONICA and 3PMFs studies.

  19322589   Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study

  19822564   Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types

  20080751   Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.

  20299471   FTO genetic variation and association with obesity in West Africans and African Americans.

  20362563   A FTO variant and risk of acute coronary syndrome.

  20381893   The genetics of obesity: FTO leads the way.

  20404173   A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.

  20442772   Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.

  20502638   Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.

  20664633   Lack of association between a new tag SNP in the FTO gene and BMI in Czech-Slavonic population.

  20717169   FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males.

  20875147   Obesity and the brain: a possible genetic link.

  20945952   FTO variant, energy intake, physical activity and basal metabolic rate in Caucasians. The HAPIEE study.

  20945953   Body mass index change in females after short-time life style intervention is not dependent on the FTO polymorphisms.

  21076408   Overexpression of Fto leads to increased food intake and results in obesity.

  21102551   Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

  21124985   Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.

  21150882   Replication of genetic variants from genome-wide association studies with metabolic traits in an island population of the Adriatic coast of Croatia.

  21283731   FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.

  21317302   FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans.

  21318054   Rs9939609 variant of the fat mass and obesity-associated gene and trunk obesity in adolescents.

  21552555   A genome-wide association study on obesity and obesity-related traits.

  21637715   Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.

  21651756   FTO gene polymorphisms and obesity risk: a meta-analysis.

  21720422   Differences in the heritability of growth and growth velocity during infancy and associations with FTO variants.

  21778217   Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study.

  21788373   The FTO gene polymorphism is associated with end-stage renal disease: two large independent case-control studies in a general population.

  21919686   Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population.

  21986706   The association of variants in the FTO gene with longitudinal body mass index profiles in non-Hispanic white children and adolescents.

  22030988   FTO risk haplotype among early onset and severe obesity cases in a population of western Spain.

  22084931   Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.

  22109280   Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

  22157232   Lack of an association between three tagging SNPs within the FTO gene and smoking behavior.

  22187296   Variants of the FTO gene in obese children and their impact on body composition and metabolism before and after lifestyle intervention.

  22189543   Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis.

  22503908   Association between FTO 1st intron tagging variant and telomere length in middle aged females. 3PMFs study.

  22614171   Appetite regulation genes are associated with body mass index in black South African adolescents: a genetic association study.

  23136261   Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.

  23201545   FTO and MC4R gene variants determine BMI changes in children after intensive lifestyle intervention.

  23236435   Fat mass and obesity associated gene (FTO) expression is regulated negatively by the transcription factor Foxa2.

  23535729   Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

  23535825   Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.

  23577239   Genetics of obesity and type 2 diabetes in African Americans.

  23593120   Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

  23771786   Genetic variants in the fat mass- and obesity-associated (FTO) gene are associated with alcohol dependence.

  23799528   Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24106974   Association between fat-mass-and-obesity-associated (FTO) gene and hip fracture susceptibility.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24392269   Gene-Lifestyle Interactions in Obesity.

  24719615   Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  24879436   Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

  24898142   Fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults.

  24941967   Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.

  25387436   Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview.

  25477898   Replication of obesity and diabetes-related SNP associations in individuals from Yucatán, México.

  25542809   Common variations in the FTO gene and obesity in Thais: a family-based study.

  25862352   Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures.

  26440677   Association of FTO and IRX3 genetic variants to obesity risk in north India.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26691922   Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases.

  26726774   Gender-Dependent Association of FTO Polymorphisms with Body Mass Index in Mexicans.

  26727661   FTO modulates fibrogenic responses in obstructive nephropathy.

  26740239   A patient with a novel homozygous missense mutation in FTO and concomitant nonsense mutation in CETP.

  26772723   Gene variants at FTO, 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men.

  26884359   Genetic predisposition to ductal carcinoma in situ of the breast.

  27117709   Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

  27168919   Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population.

  27196486   FTO rs 9939609 SNP Is Associated With Adiponectin and Leptin Levels and the Risk of Obesity in a Cohort of Romanian Children Population.

  27211558   Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study.

  27237450   Lack of Association between NYD-SP18 Variant and Obesity. The Health Alcohol and Psychosocial Factors in Eastern Europe Study.

  27241637   Is fat mass & obesity-associated (FTO) gene master regulator of obesity ?

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27478388   Assessing the Causality Factors in the Association between (Abdominal) Obesity and Physical Activity among the Newfoundland Population-A Mendelian Randomization Analysis.

  28253266   Association of OGG1 and MTHFR polymorphisms with age-related cataract: A systematic review and meta-analysis.

  28603074   FTO gene polymorphisms (rs9939609 and rs17817449) as predictors of Type 2 Diabetes Mellitus in obese Iraqi population.

  28690685   Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study.

  28954439   Mediterranean Dietary Pattern Adherence Modify the Association between FTO Genetic Variations and Obesity Phenotypes.

  29154870   The FTO variant is associated with chronic complications of diabetes mellitus in Czech population.

  29273742   The interaction of fat mass and obesity associated gene polymorphisms and dietary fiber intake in relation to obesity phenotypes.

  29382703   Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.

  29540276   Higher prevalence of FTO gene risk genotypes AA rs9939609, CC rs1421085, and GG rs17817449 and saliva containing Staphylococcus aureus in obese women in Croatia.

  29622662   Potential genetic polymorphisms predicting polycystic ovary syndrome.

  29657248   Association of fat mass and obesity-associated and retinitis pigmentosa guanosine triphosphatase (GTPase) regulator-interacting protein-1 like polymorphisms with body mass index in Chinese women.

  29937877   Analysis of SNPs of MC4R, GNB3 and FTO gene polymorphism in obese Saudi subjects.

  30063936   Association of Native American ancestry and common variants in ACE, ADIPOR2, MTNR1B, GCK, TCF7L2 and FTO genes with glycemic traits in Colombian population.

  30091536   Assessment of the FTO gene polymorphisms in male patients with metabolic syndrome.