Normal allele: AA
Common variant of the calcium-sensitive receptor gene associated with total serum calcium levels. Associated with multiple stones in calcium nephrolithiasis.
Polymorphism rs17251221 is related to topics like this:
Research and publications:
20661308 Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.
20700443 Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
20705733 Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
21966463 A genetic polymorphism (rs17251221) in the calcium-sensing receptor gene (CASR) is associated with stone multiplicity in calcium nephrolithiasis.
25270285 A genetic variant (rs17251221) in the calcium-sensing receptor relates to hepatocellular carcinoma susceptibility and clinical outcome treated by transcatheter hepatic arterial chemoembolization (TACE) therapy.
26252839 A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility.
26407952 Calcium intake, polymorphisms of the calcium-sensing receptor, and recurrent/aggressive prostate cancer.
26929638 Genetic polymorphisms of CASR and cancer risk: evidence from meta-analysis and HuGE review.
29387985 Genetic polymorphism of calcium-sensing receptor in women with breast cancer.
29695932 Quantitative assessment of the clinical susceptibility of calcium-sensing receptor polymorphisms in cancer patients.
33956883 Genetic polymorphisms as prognostic factors for recurrent kidney stones: A systematic review and meta-analysis.