Upload the DNA data file of the test

23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage

and get an enhanced
personalized health report
free without registration

Files accepted .txt, .csv, .zip, .csv.gz

File data is not stored on the server

SNP information rs17070145

RS17070145

Normal allele: TT

The KIBRA gene variant is associated with episodic memory in healthy older adults. Carriers of the KIBRA rs17070145 T allele had 24% better performance on random recall 5 minutes after word presentation and 19% better performance on random recall 24 hours after word presentation than non-carriers.

Polymorphism rs17070145 is related to topics like this:

Memory genes

Despite being often overlooked, the brain possesses an impressive ability to restrict the creation...


Research and publications:

  17053149   Common Kibra alleles are associated with human memory performance.

  17353070   KIBRA gene variants are associated with episodic memory in healthy elderly.

  17707552   Age-related association of genetic variation in KIBRA and risk of Alzheimer's disease.

  17903297   Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.

  18194457   KIBRA genetic polymorphism influences episodic memory in later life, but does not increase the risk of mild cognitive impairment.

  18205171   Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.

  18789830   Evidence of an association between KIBRA and late-onset Alzheimer's disease.

  19397951   Association of KIBRA and memory.

  19606085   Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.

  19734545   A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

  20125193   Common genetic variation and performance on standardized cognitive tests.

  20150879   Single nucleotide polymorphism of the KIBRA gene in recurrent depressive disorders.

  20184726   Genetic variation in caspase-1 is not associated with risk of Alzheimer's disease.

  20185150   Evidence of association of KIBRA genotype with episodic memory in families of psychotic patients and controls.

  20509760   Association study of KIBRA gene with memory performance in a Japanese population.

  20552044   KIBRA: A New Gateway to Learning and Memory?

  20691427   Genetic associations of brain structural networks in schizophrenia: a preliminary study

  21185624   Association of common KIBRA variants with episodic memory and AD risk.

  21346737   Impact of common KIBRA allele on human cognitive functions.

  21643791   The role of memory-related gene polymorphisms, KIBRA and CLSTN2, on replicate memory assessment in the elderly.

  22129841   GABRA2 and KIBRA genotypes predict early relapse to substance use.

  22794909   Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI.

  23065961   Association of KIBRA with episodic and working memory: a meta-analysis.

  23266749   KIBRA gene variants are associated with synchronization within the default-mode and executive control networks.

  23733450   Aging and KIBRA/WWC1 genotype affect spatial memory processes in a virtual navigation task.

  23778582   Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.

  23926262   KIBRA polymorphism is associated with individual differences in hippocampal subregions: evidence from anatomical segmentation using high-resolution MRI.

  23927501   Why it is hard to find genes associated with social science traits: theoretical and empirical considerations.

  24190487   Age-related association of KIBRA gene polymorphism with Alzheimer's disease in Han Chinese.

  24290728   WWC1 genotype modulates age-related decline in episodic memory function across the adult life span.

  24842701   PRKCA polymorphism changes the neural basis of episodic remembering in healthy individuals.

  25146696   Association of KIBRA rs17070145 polymorphism with episodic memory in the early stages of a human neurodevelopmental disorder.

  25800888   Genetic association between KIBRA polymorphism and Alzheimer's disease in a Japanese population.

  26156558   Impact of KIBRA Polymorphism on Memory Function and the Hippocampus in Older Adults.

  26415670   Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals.

  26768155   Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression.

  27060629   Association study of KIBRA rs17070145 polymorphism with the risk of schizophrenia in the Han Chinese population.

  27123786   A role for attention during wilderness navigation: Comparing effects of BDNF, KIBRA, and CHRNA4.

  27620974   APOE and KIBRA Interactions on Brain Functional Connectivity in Healthy Young Adults.

  28380666   Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway.

  28859866   Association of KIBRA polymorphisms with risk of Alzheimer's disease: data based on 20 case-control studies.

  29032191   Aging and a genetic KIBRA polymorphism interactively affect feedback- and observation-based probabilistic classification learning.

  29375362   Age-Modulated Associations between KIBRA, Brain Volume, and Verbal Memory among Healthy Older Adults.

  29391469   KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden.

  29416687   No differences in brain microstructure between young KIBRA-C carriers and non-carriers.

  30134813   The role of KIBRA in reconstructive episodic memory.

  30729420   KIBRA polymorphism modulates gray matter volume to influence cognitive ability in the elderly.

  30953258   KIBRA T allele influences memory performance and progression of cognitive decline: a 7-year follow-up study in subjective cognitive decline and mild cognitive impairment.

  31112471   The Influence of Hippocampal Dopamine D2 Receptors on Episodic Memory Is Modulated by BDNF and KIBRA Polymorphisms.

  32057830   Interaction of COMT and KIBRA modulates the association between hippocampal structure and episodic memory performance in healthy young adults.

  32352830   Combined genetic influences on episodic memory decline in older adults without dementia.

  35017578   KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients.

  35088019   The role of the KIBRA and APOE genes in developing spatial abilities in humans.

  35972417   Thalamic gray matter volume mediates the association between KIBRA polymorphism and olfactory function among older adults: a population-based study.

Genetics and high blood pressure

Abnormally high blood pressure in the arteries, which transport blood from the heart to the rest of...

G20210A prothrombin mutation

The Prothrombin G20210A mutation, also known as Factor II mutation, is a hereditary trait that...

Schizophrenia is it genetic

A psychosis known as schizophrenia impacts an individual's thinking, sense of self, and...

en
|
de
|
fr
|
es
|
it
|
ua
|
ru

Support