Normal allele: TT
The KIBRA gene variant is associated with episodic memory in healthy older adults. Carriers of the KIBRA rs17070145 T allele had 24% better performance on random recall 5 minutes after word presentation and 19% better performance on random recall 24 hours after word presentation than non-carriers.
Polymorphism rs17070145 is related to topics like this:
Research and publications:
17053149 Common Kibra alleles are associated with human memory performance.
17353070 KIBRA gene variants are associated with episodic memory in healthy elderly.
17707552 Age-related association of genetic variation in KIBRA and risk of Alzheimer's disease.
18205171 Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.
18789830 Evidence of an association between KIBRA and late-onset Alzheimer's disease.
19397951 Association of KIBRA and memory.
19606085 Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.
19734545 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
20125193 Common genetic variation and performance on standardized cognitive tests.
20150879 Single nucleotide polymorphism of the KIBRA gene in recurrent depressive disorders.
20184726 Genetic variation in caspase-1 is not associated with risk of Alzheimer's disease.
20509760 Association study of KIBRA gene with memory performance in a Japanese population.
20552044 KIBRA: A New Gateway to Learning and Memory?
20691427 Genetic associations of brain structural networks in schizophrenia: a preliminary study
21185624 Association of common KIBRA variants with episodic memory and AD risk.
21346737 Impact of common KIBRA allele on human cognitive functions.
22129841 GABRA2 and KIBRA genotypes predict early relapse to substance use.
22794909 Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI.
23065961 Association of KIBRA with episodic and working memory: a meta-analysis.
23733450 Aging and KIBRA/WWC1 genotype affect spatial memory processes in a virtual navigation task.
24190487 Age-related association of KIBRA gene polymorphism with Alzheimer's disease in Han Chinese.
24290728 WWC1 genotype modulates age-related decline in episodic memory function across the adult life span.
24842701 PRKCA polymorphism changes the neural basis of episodic remembering in healthy individuals.
25800888 Genetic association between KIBRA polymorphism and Alzheimer's disease in a Japanese population.
26156558 Impact of KIBRA Polymorphism on Memory Function and the Hippocampus in Older Adults.
26768155 Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression.
27123786 A role for attention during wilderness navigation: Comparing effects of BDNF, KIBRA, and CHRNA4.
27620974 APOE and KIBRA Interactions on Brain Functional Connectivity in Healthy Young Adults.
29416687 No differences in brain microstructure between young KIBRA-C carriers and non-carriers.
30134813 The role of KIBRA in reconstructive episodic memory.
30729420 KIBRA polymorphism modulates gray matter volume to influence cognitive ability in the elderly.
32352830 Combined genetic influences on episodic memory decline in older adults without dementia.
35088019 The role of the KIBRA and APOE genes in developing spatial abilities in humans.