Normal allele: AA
The A allele of the rs16147 variant causes a better metabolic response in terms of insulin resistance and basal insulin secondary to weight loss on two different hypocaloric diets in obese subjects, with improvement being greater on the Mediterranean diet.
Polymorphism rs16147 is related to topics like this:
Research and publications:
18385673 Genetic variation in human NPY expression affects stress response and emotion.
19119412 Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.
19566775 Association between neuropeptide Y gene and its receptor Y1 gene and methamphetamine dependence.
21300944 Emotion processing, major depression, and functional genetic variation of neuropeptide Y.
21333900 The role of genetics in IBS
21481845 Sex-specific role for adenylyl cyclase type 7 in alcohol dependence.
21658613 Host genetics in follicular lymphoma.
21728034 Methamphetamine-associated psychosis.
22011682 Pharmacogenetic approaches to the treatment of alcohol addiction.
23793356 Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.
24596569 Gene-environment interactions and intermediate phenotypes: early trauma and depression.
26156739 Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial.
26441327 Neuropeptide Y: A stressful review.
31197951 Neuropeptide Y Gene × Environment Interaction Predicts Resilience and Positive Future Focus.
33170161 Genetic test for the prescription of diets in support of physical activity.
34480216 Nutrigenetic variants and response to diet/lifestyle intervention in obese subjects: a pilot study.