SNP information rs1558902

Research and publications:

  18379722   Variations in the FTO gene are associated with severe obesity in the Japanese

  19557197   NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

  20075932   Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese.

  20421936   Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

  20430937   Fine mapping of the association with obesity at the FTO locus in African-derived populations.

  20703240   Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.

  20935630   Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

  21357378   Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer.

  21443588   Association between the FTO gene and overweight in Japanese children and adolescents.

  21466928   Genetics and epigenetics of obesity.

  21778217   Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study.

  21935397   Genome-wide population-based association study of extremely overweight young adults--the GOYA study.

  21976109   Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics Study.

  22041983   Recapitulation of genome-wide association studies on body mass index in the Korean population.

  22189543   Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis.

  22222230   FTO gene polymorphisms and platelet counts in a general Japanese population.

  22235250   Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height.

  22504289   FTO, abdominal adiposity, fasting hyperglycemia associated with elevated HbA1c in Japanese middle-aged women.

  22747683   Genetic variants associated with breast size also influence breast cancer risk.

  22891219   FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.

  23254338   FTO first intron rs1558902 variant and platelets count in white middle-aged women: prague pre- and post-menopausal females (3PMFs) study.

  23316347   Copy number variants in obesity-related syndromes: review and perspectives on novel molecular approaches.

  23471855   The genetics of childhood obesity and interaction with dietary macronutrients.

  23917806   Lack of association between DRD2 and OPRM1 genotypes and adiposity.

  24084939   A common biological basis of obesity and nicotine addiction.

  24106974   Association between fat-mass-and-obesity-associated (FTO) gene and hip fracture susceptibility.

  24278475   FTO gene variant and risk of overweight and obesity among children and adolescents: a systematic review and meta-analysis.

  24879436   Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

  24911064   Association of FTO polymorphisms with obesity and metabolic parameters in Han Chinese adolescents.

  24978468   Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups.

  24983943   Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study.

  24992585   Polygenic risk predicts obesity in both white and black young adults.

  25112650   Testing deviation from additivity in the Tukey model using shrinkage: Application to longitudinal adjustment.

  25269698   Obesity and the risk of adenocarcinoma of the esophagus and Barrett's esophagus: a Mendelian randomized trial.

  25548176   Cohort of birth modifies the association between FTO genotype and BMI.

  25649116   Mixture SNPs effect on phenotype in genome-wide association studies.

  25761503   Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.

  26193063   Are obesity risk genes associated with binge eating in adolescence?

  26374450   Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age.

  26614692   Genetic markers as instrumental variables.

  26674805   Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR).

  26683835   Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study.

  26800887   Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study.

  26821332   Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).

  26833246   New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

  26835600   GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.

  26848030   Effects of Obesity Related Genetic Variations on Visceral and Subcutaneous Fat Distribution in a Chinese Population.

  26961502   Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.

  27286809   Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.

  27336604   Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.

  27351487   Obesity and Multiple Sclerosis: A Mendelian Randomization Study.

  27455349   A thrifty variant in CREBRF strongly influences body mass index in Samoans.

  27551723   Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

  27560134   FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?

  27596730   Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index.

  27696742   Genome-Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians.

  27820839   FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men.

  27846319   Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology.

  27920511   Relationships between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men - a preliminary study.

  27974350   Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization.

  28528403   Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.

  28662178   Genetic association of FTO/IRX region with obesity and overweight in the Polish population.

  28964830   Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study.

  29212175   The role of established East Asian obesity-related loci on pediatric leptin levels highlights a neuronal influence on body weight regulation in Chinese children and adolescents: the BCAMS study.

  29484031   FTO genotype, dietary protein intake, and body weight in a multiethnic population of young adults: a cross-sectional study.

  29525920   Lack of association between FTO gene variations and metabolic healthy obese (MHO) phenotype: Tehran Cardio-metabolic Genetic Study (TCGS).

  29548861   Familial aggregation and linkage analysis with covariates for metabolic syndrome risk factors.

  29652634   Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

  29654630   Physical activity modifies the FTO effect on body mass index change in Japanese adolescents.

  29657248   Association of fat mass and obesity-associated and retinitis pigmentosa guanosine triphosphatase (GTPase) regulator-interacting protein-1 like polymorphisms with body mass index in Chinese women.

  30091536   Assessment of the FTO gene polymorphisms in male patients with metabolic syndrome.

  30584432   Genetic Identification for Non-Communicable Disease: Findings from 20 Years of the Tehran Lipid and Glucose Study.

  30764585   The Interaction between Genetic Polymorphisms in FTO and TCF7L2 Genes and Dietary Intake with Regard to Body Mass and Composition: An Exploratory Study.

  31124039   FTO gene polymorphisms and obesity risk in Chinese population: a meta-analysis.

  32053666   Fat mass and obesity-associated gene polymorphisms, pre-diagnostic plasma adipokine levels and the risk of colorectal cancer: The Japan Public Health Center-based Prospective Study.

  32103374   A novel variant near LSP1P3 is associated with knee osteoarthritis in the Chinese population.

  32384785   Applicability of Obesity-Related SNPs and their Effect Size Measures Defined on Populations with European Ancestry for Genetic Risk Estimation among Roma.

  32948839   GWA-based pleiotropic analysis identified potential SNPs and genes related to type 2 diabetes and obesity.

  33100325   Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study.

  33170161   Genetic test for the prescription of diets in support of physical activity.

  33594455   Validation of BMI genetic risk score and DNA methylation in a Korean population.

  33633342   Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.

  33753148   Association of FTO gene methylation with incident type 2 diabetes mellitus: A nested case-control study.

  35806402   The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis.