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SNP information rs1295686

RS1295686

Normal allele: CC

IL13 gene polymorphism modifies the effect of tobacco smoke exposure on persistent wheezing and asthma in childhood.

Polymorphism rs1295686 is related to topics like this:

Is asthma hereditary

Asthma is a respiratory condition that involves inflammation of the airways and recurring episodes...


Research and publications:

  15660293   No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  17303794   Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.

  17346294   IL13 gene polymorphism association with cord serum immunoglobulin E.

  18056382   Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.

  18186920   IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.

  18410415   Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.

  18625055   Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18687755   Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  19578876   The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.

  19956101   Overview of the Rapid Response data

  19956102   Evidence for association of the TCF7 locus with type I diabetes.

  20015396   Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.

  20159242   Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.

  20403202   Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study.

  20860503   A large-scale, consortium-based genomewide association study of asthma.

  20952689   Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma

  21050946   Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE.

  21111021   Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.

  21320344   Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  21995669   A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS.

  22075330   A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22180854   Polymorphisms in Th1/Th2 cytokine genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma.

  22197932   Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

  22357570   The Peru Urban versus Rural Asthma (PURA) Study: methods and baseline quality control data from a cross-sectional investigation into the prevalence, severity, genetics, immunology and environmental factors affecting asthma in adolescence in Peru

  22574126   Functional polymorphisms in IL13 are protective against high Schistosoma mansoni infection intensity in a Brazilian population.

  22769019   Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population.

  22844404   Evidence of associations between cytokine genes and subjective reports of sleep disturbance in oncology patients and their family caregivers.

  23028483   Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.

  23055793   Differential allelic expression of IL13 and CSF2 genes associated with asthma.

  23755072   Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma.

  23886662   A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

  24502445   Cytokine candidate genes predict the development of secondary lymphedema following breast cancer surgery.

  24838642   Single nucleotide polymorphisms predisposing to asthma in children of Mauritian Indian and Chinese Han ethnicity.

  25304131   Associations between cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression in patients prior to breast cancer surgery.

  25488688   Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.

  25535857   Cytokine polymorphisms and plasma levels are associated with sleep onset insomnia in adults living with HIV/AIDS.

  26365633   Lack of association between RAD50-IL13 polymorphisms and pediatric asthma susceptibility in Northeastern Han Chinese.

  26667837   Polymorphisms in Host Immunity-Modulating Genes and Risk of Invasive Aspergillosis: Results from the AspBIOmics Consortium.

  26986131   Human Cytokine Genetic Variants Associated With HBsAg Reverse Seroconversion in Rituximab-Treated Non-Hodgkin Lymphoma Patients.

  27167201   Can an IL13 -1112 C/T (rs1800925) polymorphism predict responsiveness to neoadjuvant chemoradiotherapy and survival of Chinese Han patients with locally advanced rectal cancer?

  27417569   Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases.

  27555379   Genetic Contributions of Inflammation to Depression.

  27624002   Allergy-specific Phenome-Wide Association Study for Immunogenes in Turkish Children.

  27708669   Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study.

  28057889   Association between IL-13 +1923C/T polymorphism and asthma risk: a meta-analysis based on 26 case-control studies.

  28544327   Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy.

  28871955   [The polymorphisms of IL-13 rs848G/T and rs1295686A/G in Guangxi population of China and comparative analysis].

  29017771   Association of interleukin 13 gene polymorphisms and plasma IL 13 level with risk of systemic lupus erythematosus.

  29211635   Association of IL-13 rs20541 and rs1295686 variants with symptomatic asthma in a Saudi Arabian population.

  29985321   Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry.

  31085105   Genetic Variants Associated with Cancer Pain and Response to Opioid Analgesics: Implications for Precision Pain Management.

  31129315   Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.

  31475028   Host Genetic Determinants of Hepatitis B Virus Infection.

  32522041   No Significant Effects of IL-6 and IL-13 Gene Variants on Tuberculosis Susceptibility in the Chinese Population.

  34851809   Convergent Evidence Supports TH2LCRR as a Novel Asthma Susceptibility Gene.

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19956109   Type I Diabetes Genetics Consortium Rapid Response Family-Based Candidate Gene Study: Strategy, Gene Selection, and Key Findings.

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