SNP information rs12953717

Research and publications:

  18231913   Lack of a relationship between the common 18q24 variant rs12953717 and risk of chronic lymphocytic leukemia.

  18372901   Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

  19011631   Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

  19155440   Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.

  19357349   Association of common genetic variants in SMAD7 and risk of colon cancer.

  19395656   The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression.

  19562778   Wnt antagonist gene polymorphisms and renal cancer.

  19843678   Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

  20124488   Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.

  20659471   Genetic heterogeneity in colorectal cancer associations between African and European americans.

  21036793   Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

  21068203   Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk.

  21088106   Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway.

  21179028   Replication study of SNP associations for colorectal cancer in Hong Kong Chinese.

  21221812   A risk-associated single nucleotide polymorphism of SMAD7 is common to colorectal, gastric, and lung cancers in a Han Chinese population.

  21365634   Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer.

  21387313   Genetic variation in bone morphogenetic protein and colon and rectal cancer.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  23949881   SMAD7 rs12953717 polymorphism contributes to increased risk of colorectal cancer.

  24448986   Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  27186328   Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality.

  28070019   SMAD7 polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies.

  29119627   Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery.

  29156846   S100A14 rs11548103 G>A polymorphism is associated with a decreased risk of esophageal cancer in a Chinese population.

  29228715   Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

  30337837   Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  33512737   A case-control study examining the association of smad7 and TLR single nucleotide polymorphisms on the risk of colorectal cancer in ulcerative colitis.