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SNP information rs1159918

RS1159918

Normal allele: AA

The ADH1B Arg47His polymorphism is associated with alcohol response, consumption and dependence.

Polymorphism rs1159918 is related to topics like this:

Alcoholism genes

Although alcohol is widely consumed, excessive use can lead to serious physical, psychological, and...


Research and publications:

  17273965   Evidence of positive selection on a class I ADH locus.

  18331377   Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.

  18996923   Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.

  19193628   ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

  19298322   Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans.

  20089146   The ADH1B Arg47His polymorphism in east Asian populations and expansion of rice domestication in history.

  20729852   A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

  21083667   Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.

  21143251   A candidate gene association study of alcohol consumption in young women.

  21168396   Variation in the ADH1B proximal promoter affects expression.

  21592108   Diversification of the ADH1B gene during expansion of modern humans.

  21635275   Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample.

  21940907   Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk of head and neck cancer.

  23895337   Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample.

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Heart disease genetic

Although genetics can be a major factor in the development of certain heart diseases, individuals...

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