SNP information rs1138272

Research and publications:

  15817713   Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations

  16582078   Influence of glutathione-S-transferase (GSTM1, GSTP1, GSTT1) and cytochrome p450 (CYP1A1, CYP2D6) polymorphisms on numbers of basal cell carcinomas (BCCs) in families with the naevoid basal cell carcinoma syndrome.

  17160896   Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.

  17194543   Variants of the glutathione S-transferase classes mu, omega, pi, and theta and smoking in Parkinson's disease.

  17601350   A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

  17686149   Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery.

  18191955   Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools

  18449058   Maternal smoking and oral clefts: the role of detoxification pathway genes.

  18559526   Glutathione s-transferase p1: gene sequence variation and functional genomic studies.

  18601742   Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.

  18709160   Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease

  18768509   Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.

  18776599   Susceptibility genes for gentamicin-induced vestibular dysfunction.

  18854777   Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.

  18992148   Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study

  19076156   Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.

  19442035   Pharmacogenomics of platinum-based chemotherapy in NSCLC.

  19822571   Genetic variations in xenobiotic metabolic pathway genes, personal hair dye use, and risk of non-Hodgkin lymphoma.

  20029944   Genetic polymorphisms in the metabolic pathway and non-Hodgkin lymphoma survival.

  20049130   Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study.

  20131310   Genetic polymorphisms in cytochrome P450s, GSTs, NATs, alcohol consumption and risk of non-Hodgkin lymphoma.

  20413979   Testing haplotype-environment interactions using case-parent triads.

  20459744   Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.

  20540773   The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer.

  21179236   Analysis of candidate genes for macular telangiectasia type 2.

  21504558   Evaluation of the impact of genetic polymorphisms in glutathione-related genes on the association between methylmercury or n-3 polyunsaturated long chain fatty acids and risk of myocardial infarction: a case-control study.

  21532841   Interaction of CYP1B1, cigarette-smoke carcinogen metabolism, and lung cancer risk.

  21741876   Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk.

  21894447   Are centenarians genetically predisposed to lower disease risk?

  21914837   Childhood brain tumors and maternal cured meat consumption in pregnancy: differential effect by glutathione S-transferases.

  21967774   Glutathione enzyme and selenoprotein polymorphisms associate with mercury biomarker levels in Michigan dental professionals.

  22044695   Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer.

  22277159   Implications for health and disease in the genetic signature of the Ashkenazi Jewish population.

  22301281   Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk.

  22357570   The Peru Urban versus Rural Asthma (PURA) Study: methods and baseline quality control data from a cross-sectional investigation into the prevalence, severity, genetics, immunology and environmental factors affecting asthma in adolescence in Peru

  22454423   Genetic variations and patient-reported quality of life among patients with lung cancer.

  22487578   Association of glutathione S-transferase pi isoform single-nucleotide polymorphisms with exudative age-related macular degeneration in a Chinese population.

  22655231   Sequence Variants and the Risk of Head and Neck Cancer: Pooled Analysis in the INHANCE Consortium.

  22655262   Exposure to Polycyclic Aromatic Hydrocarbons Among Never Smokers in Golestan Province, Iran, an Area of High Incidence of Esophageal Cancer - a Cross-Sectional Study with Repeated Measurement of Urinary 1-OHPG in Two Seasons.

  22661588   Antioxidant enzyme polymorphisms and neuropsychological outcomes in medulloblastoma survivors: a report from the Childhood Cancer Survivor Study.

  22674470   Phenanthrene metabolism in smokers: use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation.

  22868256   A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen.

  23066387   Association study of genes associated to asthma in a specific environment, in an asthma familial collection located in a rural area influenced by different industries.

  23175176   Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.

  23179585   Possible contribution of GSTP1 and other xenobiotic metabolizing genes to vitiligo susceptibility.

  23226154   Polymorphisms of Phase I and Phase II Enzymes and Breast Cancer Risk.

  23433810   Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia.

  23663310   Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.

  23880893   Traffic, asthma and genetics: combining international birth cohort data to examine genetics as a mediator of the effects of traffic-related air pollution on childhood asthma.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24260161   Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes.

  24340057   Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy.

  24465030   GSTP1 and TNF Gene variants and associations between air pollution and incident childhood asthma: the traffic, asthma and genetics (TAG) study.

  24610081   Associations between SNPs within antioxidant genes and the risk of prostate cancer in the Siberian region of Russia.

  24895604   Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25110414   Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years.

  25266489   Genetic polymorphisms of VIP variants in the Tajik ethnic group of northwest China.

  25383449   Docetaxel-induced neuropathy: a pharmacogenetic case-control study of 150 women with early-stage breast cancer.

  25515186   GSTM1, GSTP1, and GSTT1 genetic variability in Turkish and worldwide populations.

  25592234   Genetic variability of DNA repair mechanisms and glutathione-S-transferase genes influences treatment outcome in osteosarcoma.

  25719551   The role of genotypes that modify the toxicity of chemical mutagens in the risk for myeloproliferative neoplasms.

  25881102   Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer.

  26091847   Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

  26451011   Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.

  26858644   Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

  26942037   Genetic profile, environmental exposures and their interactions in Parkinson's disease.

  27006283   Xenobiotic Pathway Gene Polymorphisms Associated with Gastric Cancer in High Risk Mizo-Mongoloid Population, Northeast India.

  27043589   The Association between Gene-Environment Interactions and Diseases Involving the Human GST Superfamily with SNP Variants.

  27069453   Antioxidant defence-related genetic variants are not associated with higher risk of secondary thyroid cancer after treatment of malignancy in childhood or adolescence.

  27193053   Exploring the interaction among EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population.

  27233804   Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

  27277477   Correlation between prostate volume and single nucleotide polymorphisms implicated in the steroid pathway.

  27608007   Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients.

  27655273   Fire Usage and Ancient Hominin Detoxification Genes: Protective Ancestral Variants Dominate While Additional Derived Risk Variants Appear in Modern Humans.

  27679545   Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma.

  27729156   Analysis of genetic and non genetic risk factors for cisplatin ototoxicity in pediatric patients.

  27883295   Identification of novel SNPs associated with risk and prognosis in patients with castration-resistant prostate cancer.

  28158543   Supporting precision medicine by data mining across multi-disciplines: an integrative approach for generating comprehensive linkages between single nucleotide variants (SNVs) and drug-binding sites.

  28827732   Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.

  28844971   Genetically driven antioxidant capacity in a Caucasian Southeastern European population.

  29085212   Genetic biomarkers for hepatocellular cancer risk in a caucasian population.

  29371927   Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy.

  29505746   Association of N-acetyltransferase-2 and glutathione S-transferase polymorphisms with idiopathic male infertility in Vietnam male subjects.

  29771645   Common polymorphisms in antioxidant genes are associated with diabetic nephropathy in Type 2 diabetes patients.

  29875076   GSTP1 c.341C>T gene polymorphism increases the risk of oral squamous cell carcinoma.

  30210047   Pharmacogenomic markers of glucocorticoid response in the initial phase of remission induction therapy in childhood acute lymphoblastic leukemia.

  30452466   Characterization of ADME genes variation in Roma and 20 populations worldwide.

  30740061   Comprehensive Analysis of the Association Between the rs1138272 Polymorphism of the GSTP1 Gene and Cancer Susceptibility.

  31275451   Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart Failure.

  31428123   Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations.

  31506802   The Impact of Beta-Catenin and glutathione-S-transferase Gene Polymorphisms on the Treatment Results and Survival of Multiple Myeloma Patients.

  32125559   Correlation of GSTP1 gene variants of male Iraqi waterpipe (Hookah) tobacco smokers and the risk of lung cancer.

  32183092   GSTP1 rs1138272 Polymorphism Affects Prostate Cancer Risk.

  32334487   Association analysis of rs1695 and rs1138272 variations in GSTP1 gene and breast cancer susceptibility.

  33425072   Genetic Variability of Antioxidative Mechanisms and Cardiotoxicity after Adjuvant Radiotherapy in HER2-Positive Breast Cancer Patients.

  33544514   The role of polymorphisms in glutathione-related genes in asbestos-related diseases.

  33794901   Cord blood acrylamide levels and birth size, and interactions with genetic variants in acrylamide-metabolising genes.