SNP information rs1128503

Research and publications:

  15197162   Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene.

  16999857   ABCB1 genotypes and haplotypes in patients with dementia and age-matched non-demented control patients.

  17548681   MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.

  17913323   ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.

  18213362   Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array.

  18424454   ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence.

  18547414   Genotyping panel for assessing response to cancer chemotherapy

  18698231   Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

  18725235   Bidirectional translational research: Progress in understanding addictive diseases.

  18812236   No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population.

  19107781   Association between ABCB1/MDR1 gene polymorphism and Crohn's disease: a gene-wide study in a pediatric population.

  19155191   Opiate and cocaine addiction: from bench to clinic and back to the bench.

  19285141   Genetic determinants of target and novelty-related event-related potentials in the auditory oddball response

  19437139   ABCB1 single nucleotide polymorphisms in the Brazilian population.

  19694740   No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.

  19740399   Influence of ABCB1 polymorphisms and haplotypes on tacrolimus nephrotoxicity and dosage requirements in children with liver transplant.

  19819348   Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.

  19844206   Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.

  19890215   CYP2C19 genetic variants affect nelfinavir pharmacokinetics and virologic response in HIV-1-infected children receiving highly active antiretroviral therapy.

  19896927   Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms.

  19916993   A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.

  19924384   Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.

  20170205   Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

  20177420   Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer

  20201854   Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

  20214406   Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II.

  20216335   Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein).

  20354687   Explaining variability in ciclosporin exposure in adult kidney transplant recipients.

  20389299   Pazopanib-induced hyperbilirubinemia is associated with the UGT1A1 polymorphism of Gilbert's syndrome.

  20505666   Donor P-gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long-term follow-up.

  20532504   Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.

  20533057   ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer.

  20602618   Irinotecan pharmacogenomics.

  20628376   Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients.

  20801494   Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.

  20847277   Genotyping of DNA samples isolated from formalin-fixed paraffin-embedded tissues using preamplification.

  20921971   Mapping genes that predict treatment outcome in admixed populations.

  20981002   Breaking barriers in the genomics and pharmacogenetics of drug addiction

  21048526   Doxorubicin pathways: pharmacodynamics and adverse effects.

  21102498   Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients.

  21119772   A Hybrid Machine Learning Method for Fusing fMRI and Genetic Data: Combining both Improves Classification of Schizophrenia.

  21122163   The pharmacogenetics of imanitib.

  21172166   Pharmacogenetics of antidepressant response.

  21197301   Recent advances in the use of opioids for cancer pain.

  21219401   Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients.

  21311724   Genetic polymorphisms of ATP-binding cassette (ABC) proteins, overall survival and drug toxicity in patients with Acute Myeloid Leukemia.

  21358750   Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment.

  21441680   Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians.

  21553324   Polymorphisms of the MDR1 and MIF genes in children with nephrotic syndrome.

  21686133   Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome.

  21687501   Pharmacogenetics of antidepressants.

  21705081   Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.

  21712189   Analysis of pharmacogenetic traits in two distinct South African populations.

  21747585   Pharmacogenomic association study on the role of drug metabolizing, drug transporters and drug target gene polymorphisms in drug-resistant epilepsy in a north Indian population.

  21747587   Corpora amylacea deposition in the hippocampus of patients with mesial temporal lobe epilepsy: A new role for an old gene?

  21790905   CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction.

  21806386   Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients.

  21840870   Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy.

  21896346   Polymorphisms in genes that regulate cyclosporine metabolism affect cyclosporine blood levels and clinical outcomes in patients who receive allogeneic hematopoietic stem cell transplantation.

  21999196   Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers.

  22015057   Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study.

  22016816   Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.

  22094953   Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients.

  22110582   Association of MDR1 gene SNPs and haplotypes with the tacrolimus dose requirements in Han Chinese liver transplant recipients.

  22134106   ABCB1 haplotype is associated with major molecular response in chronic myeloid leukemia patients treated with standard-dose of imatinib.

  22136368   Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.

  22257384   Role of ABC transporters in cancer chemotherapy.

  22306099   Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population.

  22358301   ABCB1 genetic variation and P-glycoprotein expression/activity in a cohort of Brazilian acute myeloid leukemia patients.

  22445700   The impact of drug metabolizing enzyme polymorphisms on outcomes after antenatal corticosteroid use.

  22527101   CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel.

  22569204   PharmGKB summary: phenytoin pathway.

  23050008   Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population.

  23056078   Gene polymorphisms of ABC transporters are associated with clinical outcomes in children with acute lymphoblastic leukemia.

  23064017   Donor ABCB1 variant associates with increased risk for kidney allograft failure.

  23067778   Function of the blood-brain barrier P-glycoprotein in healthy people and patients with Alzheimer's disease: the influence of ABCB1 gene polymorphism.

  23073467   Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients.

  23133420   Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.

  23133441   ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients.

  23188198   ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression.

  23226062   ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics.

  23252947   Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy.

  23272163   SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia.

  23319877   Association between ABCB1 Polymorphisms and Ischemic Stroke in Korean Population.

  23356581   P-glycoprotein (PGP) polymorphisms and sexual dysfunction in female patients with depression and SSRI-associated sexual side effects.

  23407853   Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers.

  23443032   Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations.

  23462807   Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib.

  23527191   Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone.

  23556452   Pharmacogenetics, enzyme probes and therapeutic drug monitoring as potential tools for individualizing taxane therapy.

  23632726   Association of OPRM1 and COMT single-nucleotide polymorphisms with hospital length of stay and treatment of neonatal abstinence syndrome.

  23633119   Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipients.

  23687985   The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case-control studies.

  23738951   Population pharmacokinetic and pharmacogenetic analysis of tacrolimus in paediatric liver transplant patients.

  23766564   Pharmacogenetics of chronic pain and its treatment.

  23896815   Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.

  23911231   Statin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes.

  23917080   ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas.

  23922006   PharmGKB summary: cyclosporine and tacrolimus pathways.

  23922910   A clinical tool for reducing central nervous system depression among neonates exposed to codeine through breast milk.