SNP information rs10818488

Research and publications:

  17880261   A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis.

  18432273   STAT4 but not TRAF1/C5 variants influence the risk of developing rheumatoid arthritis and systemic lupus erythematosus in Colombians.

  18434327   Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

  18593758   The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis.

  18625278   Association of a TRAF1 and a STAT4 gene polymorphism with increased risk for rheumatoid arthritis in a genetically homogeneous population.

  18648537   A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2

  18759306   Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study.

  18987647   Rheumatoid arthritis: a view of the current genetic landscape

  19302705   Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.

  19336421   Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese.

  19433411   The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

  19445664   Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

  19565500   Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis

  19674979   Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

  19918040   Lack of association between TRAF1/C5 gene polymorphisms and biopsy-proven giant cell arteritis.

  20030635   The TRAF1/C5 locus confers risk for familial and severe alopecia areata.

  20205706   TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies.

  20219786   The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.

  20309765   Bagging optimal ROC curve method for predictive genetic tests, with an application for rheumatoid arthritis.

  20353580   Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21492465   Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population.

  21905002   Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus.

  21968398   TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey.

  22820624   Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  22927710   Genetic markers of cardiovascular disease in rheumatoid arthritis.

  23251581   Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades.

  23321589   Association study of TRAF1/C5 polymorphism (rs10818488) with susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis.

  23777930   Investigation of juvenile idiopathic arthritis susceptibility loci: results from a Greek population.

  24144456   Associations between TRAF1-C5 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

  24234752   Association between polymorphism in TRAF1/C5 gene and risk of rheumatoid arthritis: a meta-analysis.

  24338224   Lack of association between single nucleotide polymorphism rs10818488 in TRAF1/C5 region and rheumatoid arthritis in iranian population.

  25500258   TRAF1/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population.

  27306948   Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study.

  27536202   Association of the polymorphisms of TRAF1 (rs10818488) and TNFAIP3 (rs2230926) with rheumatoid arthritis and systemic lupus erythematosus and their relationship to disease activity among Egyptian patients.

  31530986   Associations of TRAF1/C5 rs10818488 and rs3761847 polymorphisms with genetic susceptibility to rheumatoid arthritis: a case-control study and updated meta-analysis.

  31570557   Association of TRAF1/C5 Locus Polymorphisms with Epilepsy and Clinical Traits in Mexican Patients with Neurocysticercosis.

  34363926   A genetic variant in the TRAF1/C5 gene lead susceptibility to active pulmonary tuberculosis by decreased TNF-α levels.

  36036499   Inflammation-related Gene Polymorphisms Associated With Childhood Acute Lymphoblastic Leukemia.