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SNP information rs10517


Normal allele: GG

A break in the oxidative stress gene, increases the risk of developing asthma.

Polymorphism rs10517 is related to topics like this:

DNA oxidation

Cancer may be linked to oxidative damage of DNA from various chemical and physical agents, but...

Research and publications:

  18632753   Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  20049212   Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS).

  20663217   Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China.

  23259684   Genetic oxidative stress variants and glioma risk in a Chinese population: a hospital-based case-control study.

  24177223   Significant interactions between maternal PAH exposure and haplotypes in candidate genes on B[a]P-DNA adducts in a NYC cohort of non-smoking African-American and Dominican mothers and newborns.

  25545243   Oxidative stress-related genetic polymorphisms are associated with the prognosis of metastatic gastric cancer patients treated with epirubicin, oxaliplatin and 5-fluorouracil combination chemotherapy.

  25729241   Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.

  26257249   Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves.

  27740732   Identification of novel variants associated with warfarin stable dosage by use of a two-stage extreme phenotype strategy.

  30237583   An exploratory study by DMET array identifies a germline signature associated with imatinib response in gastrointestinal stromal tumor.

  31854268   Impact of CYP2C9, VKORC1, ApoE and ABCB1 polymorphisms on stable warfarin dose requirements in elderly Chinese patients.

  34457036   Influence of NQO1 Polymorphisms on Warfarin Maintenance Dose: A Systematic Review and Meta-Analysis (rs1800566 and rs10517).

Omega 3 genetics

It may seem counterintuitive that substances with the names "fat" and "acid" can be beneficial for...

CPT2 disease

A condition affecting the oxidation of long-chain fatty acids, Carnitine palmitoyltransferase II...

Nuclear hormone receptors

The activated ligand-regulated transcription factors collectively known as nuclear receptors...