SNP information rs961253

Research and publications:

  19011631   Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19786869   Recent insights into the pathogenesis of colorectal cancer.

  20368424   Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.

  20501757   Low-penetrance susceptibility variants in familial colorectal cancer.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20530476   Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population.

  20585100   Genome-wide association studies of cancer.

  20628028   Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis.

  20648012   Association studies on 11 published colorectal cancer risk loci.

  20659471   Genetic heterogeneity in colorectal cancer associations between African and European americans.

  20688557   The Yin and Yang of bone morphogenetic proteins in cancer.

  21071539   Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.

  21119214   Colorectal cancer susceptibility loci in a population-based study: Associations with morphological parameters.

  21179028   Replication study of SNP associations for colorectal cancer in Hong Kong Chinese.

  21314996   Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.

  21357381   Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.

  21655089   Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

  21761138   Meta-analysis of new genome-wide association studies of colorectal cancer risk.

  22045029   Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.

  22235025   Susceptibility genetic variants associated with early-onset colorectal cancer.

  22363440   cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

  22367214   Characterization of gene-environment interactions for colorectal cancer susceptibility loci.

  22532847   Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.

  22629442   Evaluation of allele-specific somatic changes of genome-wide association study susceptibility alleles in human colorectal cancers.

  22675446   Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  22879968   Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

  22999960   Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

  23161572   BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.

  23300701   Genome-wide search for gene-gene interactions in colorectal cancer.

  23326130   Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma.

  23350875   A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.

  23434150   Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

  23537995   Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24587672   New genes emerging for colorectal cancer predisposition.

  24705330   Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.

  24727911   Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24801760   Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

  24828072   The SNP rs1883832 in CD40 gene and risk of atherosclerosis in Chinese population: a meta-analysis.

  24968322   Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.

  25956580   A colorectal cancer prediction model using traditional and genetic risk scores in Koreans.

  26078566   Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population.

  26451011   Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.

  26880076   Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers.

  27078840   Genetic Variants Associated with Colorectal Adenoma Susceptibility.

  27122668   Effects of interactions between environmental factors and KIF1B genetic variants on the risk of hepatocellular carcinoma in a Chinese cohort.

  27146020   Colorectal cancer risk genes are functionally enriched in regulatory pathways.

  27379672   Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

  27588484   Gene-gene interactions in gastrointestinal cancer susceptibility.

  28084440   Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.

  28233817   Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study.

  29547645   Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.

  30337837   Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  32022527   Synchronous and multiple renal cell carcinoma, clear cell and papillary: An approach to clinically significant genetic abnormalities.

  32928932   Genetic Colorectal Cancer and Adenoma Risk Variants Are Associated with Increasing Cumulative Adenoma Counts.