SNP information rs951266

Research and publications:

  17373692   No evidence for association between 19 cholinergic genes and bipolar disorder.

  18227835   Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking

  18618000   A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction

  18759969   In search of causal variants: refining disease association signals using cross-population contrasts

  19330903   Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  19859904   Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

  20485328   Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

  20808433   Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population

  22539395   Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

  22648373   Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.

  22837378   Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

  22899653   Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.

  23196875   Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder.

  23221128   Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  25051068   Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analyses.

  26981579   Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.

  27099524   Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  27694844   Fisher's adaptive combination method for joint analysis of multiple phenotypes in association studies.