SNP information rs861539

Research and publications:

  11059748   A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer.

  16465622   Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

  16857995   Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.

  17557904   Evaluation of genetic variation in the double-strand break repair pathway and bladder cancer risk.

  17705814   Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of northern Spain.

  18086758   Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.

  18188695   Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk of breast cancer in Cyprus.

  18191955   Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools

  18194558   A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

  18410587   Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan.

  18579371   Genetic polymorphisms in double-strand break DNA repair genes associated with risk of oral premalignant lesions.

  18582155   Association of single nucleotide polymorphisms in SOD2, XRCC1 and XRCC3 with susceptibility for the development of adverse effects resulting from radiotherapy for prostate cancer.

  18701435   Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.

  18708406   Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in China.

  18768505   Genetic susceptibility to renal cell carcinoma: the role of DNA double-strand break repair pathway.

  18830263   Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma

  18990748   International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.

  19109789   Single nucleotide polymorphisms in DNA repair genes and prostate cancer risk.

  19124499   Association and interactions between DNA repair gene polymorphisms and adult glioma.

  19127255   Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.

  19367277   Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer.

  19706757   Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.

  19815090   Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?

  19902366   Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.

  20004634   Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.

  20150366   DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.

  20226869   Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations.

  20334523   Association between normal tissue complications after radiotherapy and polymorphic variations in TGFB1 and XRCC1 genes.

  20590474   Polymorphic variants of DNA repair gene XRCC3 and XRCC7 and risk of prostate cancer: a study from North Indian population.

  20935063   Smoking and selected DNA repair gene polymorphisms in controls: systematic review and meta-analysis.

  21104022   Polymorphisms in RAD51, XRCC2 and XRCC3 genes of the homologous recombination repair in colorectal cancer--a case control study.

  21183201   DNA repair gene polymorphisms at XRCC1, XRCC3, XPD, and OGG1 loci in Maharashtrian population of central India.

  21195504   Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk.

  21332318   Identification of SNPs associated with susceptibility for development of adverse reactions to radiotherapy.

  21347786   DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy.

  21419115   DNA repair gene ERCC2 polymorphisms and risk of squamous cell carcinoma of the head and neck.

  21487324   Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21561390   Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in a Turkish population.

  21617942   Gene variants of XRCC4 and XRCC3 and their association with risk for urothelial bladder cancer.

  21647442   Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy.

  21658613   Host genetics in follicular lymphoma.

  21700777   Genetic polymorphisms of multiple DNA repair pathways impact age at diagnosis and TP53 mutations in breast cancer.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  21725594   Combined effect of polymorphisms in Rad51 and Xrcc3 on breast cancer risk and chromosomal radiosensitivity.

  21749698   Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of articledeveloping erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery.

  21877955   Involvement of single-nucleotide polymorphisms in predisposition to head and neck cancer in Saudi Arabia.

  21974800   DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.

  22272830   SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation.

  22525558   Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population.

  22655231   Sequence Variants and the Risk of Head and Neck Cancer: Pooled Analysis in the INHANCE Consortium.

  22726897   Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratio-based genetic algorithms.

  22740138   An interethnic variability and a functional prediction of DNA repair gene polymorphisms: the example of XRCC3 (p.Thr241>Met) and XPD (p.Lys751>Gln) in a healthy Tunisian population.

  22933979   Genetic polymorphisms in homologous recombination repair genes in healthy Slovenian population and their influence on DNA damage.

  23271134   Association between XRCC1 and XRCC3 polymorphisms and colorectal cancer risk: a meta-analysis of 23 case-control studies.

  23443124   XRCC3 gene polymorphism is associated with survival in Japanese lung cancer patients.

  23526128   Lack of association between XRCC3 rs861539 (C > T) polymorphism and lung cancer risks: an update meta-analysis.

  23539294   XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nucleotide polymorphisms in cervical cancer risk.

  23565320   DNA repair genotype and lung cancer risk in the beta-carotene and retinol efficacy trial.

  23663450   Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility.

  23697595   SNPs in genes implicated in radiation response are associated with radiotoxicity and evoke roles as predictive and prognostic biomarkers.

  23720673   Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.

  23982880   Comprehensive assessment of the association between DNA repair gene XRCC3 rs861539 C/T polymorphism and lung cancer risk.

  24085356   Genetic polymorphisms of XRCC3 Thr241Met (C18067T, rs861539) and bladder cancer risk: a meta-analysis of 18 research studies.

  24304418   Association of XRCC3 Thr241Met polymorphism and leukemia risk: evidence from a meta-analysis.

  24315498   Synergistic association of DNA repair relevant gene polymorphisms with the risk of coronary artery disease in northeastern Han Chinese.

  24325908   Analysis of DNA repair gene polymorphisms in glioblastoma.

  24395651   Association between XRCC3 Thr241Met SNP and systemic lupus erythematosus in Han Chinese patients in Taiwan, and a meta-analysis of healthy populations.

  24500421   Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis.

  24619222   Polymorphisms in DNA repair genes (APEX1, XPD, XRCC1 and XRCC3) and risk of preeclampsia in a Mexican mestizo population.

  24642895   The relationship between seven common polymorphisms from five DNA repair genes and the risk for breast cancer in northern Chinese women.

  24701578   The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making.

  24728564   Association between single nucleotide polymorphisms (SNPs) of XRCC2 and XRCC3 homologous recombination repair genes and triple-negative breast cancer in Polish women.

  24756092   Polymorphisms in DNA repair genes and MDR1 and the risk for non-Hodgkin lymphoma.

  24794803   XRCC3 Thr241Met (rs861539) polymorphism and leukemia risk: unresolved controversy.

  24939416   CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients.

  24940494   Association of XRCC1 and XRCC3 gene haplotypes with the development of radiation-induced fibrosis in patients with nasopharyngeal carcinoma.

  25006581   Analyzing association of the XRCC3 gene polymorphism with ovarian cancer risk.

  25178586   Polymorphisms in DNA repair genes, hair dye use, and the risk of non-Hodgkin lymphoma.

  25231222   Meat-derived carcinogens, genetic susceptibility and colorectal adenoma risk.

  25452763   Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?

  25529925   Do genetic defects of DNA repair relevant proteins alter susceptibility to hypertension? A case-control study in northeastern Han Chinese.

  25687493   Contribution of double strand break repair gene XRCC3 genotypes to nasopharyngeal carcinoma risk in Taiwan.

  25928231   Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis.

  26029010   Gene-by-Environment Interactions in Pancreatic Cancer: Implications for Prevention.

  26091483   Association between Single Nucleotide Polymorphisms in XRCC3 and Radiation-Induced Adverse Effects on Normal Tissue: A Meta-Analysis.

  26124335   Contribution of Genotype of DNA Double-strand Break Repair Gene XRCC3, Gender, and Smoking Behavior to Lung Cancer Risk in Taiwan.

  26159902   DNA Repair Gene Polymorphisms in Relation to Non-Small Cell Lung Cancer Survival.

  26254358   Contribution of X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) Genotype to Leiomyoma Risk.

  26263974   Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine.

  26264616   Association between x-ray repair cross-complementing group 3 (XRCC3) genetic polymorphisms and papillary thyroid cancer susceptibility in a Chinese Han population.

  26339569   Polymorphisms of homologous recombination RAD51, RAD51B, XRCC2, and XRCC3 genes and the risk of prostate cancer.

  26400288   DNA repair gene XRCC3 variants are associated with susceptibility to glioma in a Chinese population.

  26446325   X-ray repair cross-complementing protein 1 and 3 polymorphisms and susceptibility of breast cancer in a Jordanian population.

  26451011   Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.

  26543082   Contribution of DNA Double-strand Break Repair Gene XRCC3 Genotypes to Triple-negative Breast Cancer Risk.

  26549042   Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa.

  26590607   The relationship between five non-synonymous polymorphisms within three XRCC genes and gastric cancer risk in a Han Chinese population.

  26627042   ERCC2 polymorphisms and radiation-induced adverse effects on normal tissue: systematic review with meta-analysis and trial sequential analysis.

  26801223   Association between single nucleotide polymorphisms (SNPs) of XRCC2 and XRCC3 homologous recombination repair genes and ovarian cancer in Polish women.