SNP information rs8040868

Research and publications:

  18163978   The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.

  18165968   Identification of pharmacogenetic markers in smoking cessation therapy

  19330903   Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19789337   Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1

  19859904   Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

  20485328   Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

  20736995   Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence

  20808433   Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population

  20854418   CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences

  21606948   Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes

  21858091   In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression.

  22042234   Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.

  22280835   New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer.

  22382757   The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

  22945651   Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

  23196875   Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder.

  23251661   Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population

  25399010   Association between polymorphisms in CHRNA3 and PHACTR2 gene and environment and NSCLC risk in Chinese population.

  26831765   Association between two CHRNA3 variants and susceptibility of lung cancer: a meta-analysis.

  27835950   Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease.

  28240528   Novel Mutations of the CHRNA3 Gene in Non-Small Cell Lung Cancer in an Iranian Population.

  28553097   Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients.

  29416783   Study on polymorphisms in CHRNA5/CHRNA3/CHRNB4 gene cluster and the associated with the risk of non-small cell lung cancer.

  29879020   Association analysis of CHRNA3 polymorphisms with schizophrenia in a Chinese Han population: A case-control study.

  30060175   Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.

  31362771   CHRNA5/CHRNA3 gene cluster is a risk factor for lumbar disc herniation: a case-control study.

  27694844   Fisher's adaptive combination method for joint analysis of multiple phenotypes in association studies.