Normal allele: GG
Genetic variability in the oxytocin receptor has been linked to empathy and stress response in humans. Studies have shown that people without a break in the gene are more empathic, feel less lonely, use more sensitive parenting techniques and are less likely to have autism. The gene also correlates significantly with parenting, with people without a break in the gene being associated with a significantly more sensitive parenting style than heterozygote and homozygote carriers.
Polymorphism rs53576 is related to topics like this:
Research and publications:
15992526 Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population.
17383819 Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism.
18687882 Genetic correlates of adult attachment style.
19015103 Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting.
19515497 Oxytocin receptor polymorphisms and adult attachment style in patients with depression.
19934046 Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans.
21896752 Oxytocin receptor gene (OXTR) is related to psychological resources.
22015110 Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior.
22069391 Oxytocin receptor gene associated with the efficiency of social auditory processing.
22357335 The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy.
22372486 The role of oxytocin and oxytocin receptor gene variants in childhood-onset aggression.
22487732 Influence of COX-2 and OXTR polymorphisms on treatment outcome in treatment resistant depression.
22580735 Breastfeeding and its relation to maternal sensitivity and infant attachment.
22615702 Imaging-genetics in autism spectrum disorder: advances, translational impact, and future directions.
22846218 Sexually dimorphic effects of oxytocin receptor gene (OXTR ) variants on Harm Avoidance.
23087634 DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli.
23089921 Common oxytocin receptor gene polymorphisms and the risk for preterm birth.
23335876 Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin.
23562248 The association between the oxytocin receptor gene (OXTR) and hypnotizability.
23684879 Variant in OXTR gene and functional connectivity of the hypothalamus in normal subjects.
23708061 Neural mechanisms of oxytocin receptor gene mediating anxiety-related temperament.
23921259 A sociability gene? Meta-analysis of oxytocin receptor genotype effects in humans.
24596569 Gene-environment interactions and intermediate phenotypes: early trauma and depression.
25009457 Social bonding: regulation by neuropeptides.
25564674 Distress of ostracism: oxytocin receptor gene polymorphism confers sensitivity to social exclusion.
25637390 Oxytocin receptor gene and racial ingroup bias in empathy-related brain activity.
25773927 Association between the oxytocin receptor gene polymorphism (rs53576) and bulimia nervosa.
26106053 Severity of eating disorder symptoms related to oxytocin receptor polymorphisms in anorexia nervosa.
26121678 Association of Oxytocin Receptor Gene (OXTR) rs53576 Polymorphism with Sociality: A Meta-Analysis.
26174935 Oxytocin system social function impacts in children with attention-deficit/hyperactivity disorder.
26253726 Primate paternal care: Interactions between biology and social experience.
26322220 A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.
26488131 Attachment style and oxytocin receptor gene variation interact in influencing social anxiety.
26506050 Genetic modulation of oxytocin sensitivity: a pharmacogenetic approach.
26713079 Is Oxytocin Application for Autism Spectrum Disorder Evidence-Based?
26787430 Oxytocin receptor gene variation predicts subjective responses to MDMA.
26858594 Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits.
26869977 The Adapting Mind in the Genomic Era.
26901829 BDNF Val66Met Polymorphism Is Associated with Self-Reported Empathy.
26903639 Delay discounting, genetic sensitivity, and leukocyte telomere length.
27036876 An oxytocin receptor polymorphism predicts amygdala reactivity and antisocial behavior in men.
27317929 Effects of oxytocin administration on spirituality and emotional responses to meditation.
27497314 Variation in the oxytocin receptor gene (OXTR) is associated with differences in moral judgment.