SNP information rs4684677

Research and publications:

  12050239   Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students.

  16204371   Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.

  17389697   Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes.

  18239581   Lack of association of ghrelin precursor gene variants and percentage body fat or serum lipid profiles.

  19041386   Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

  19165163   Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.

  19593725   Association of maternally inherited GNAS alleles with African-American male birth weight.

  20010782   Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease.

  20586762   Genetic variation of the ghrelin signaling system in females with severe alcohol dependence.

  20920174   Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study.

  21448464   The ghrelin signalling system is involved in the consumption of sweets.

  22005651   Genetic association between ghrelin polymorphism and Alzheimer's disease in a Japanese population.

  23084284   A possible association between panic disorder and a polymorphism in the preproghrelingene.

  23227170   Ghrelin influences novelty seeking behavior in rodents and men.

  24340245   Adiposity, inflammation, genetic variants and risk of post-menopausal breast cancer findings from a prospective-specimen-collection, retrospective-blinded-evaluation (PRoBE) design approach.

  24619886   Glucose impairment and ghrelin gene variants are associated to cognitive dysfunction.

  25376984   Associations between ghrelin and ghrelin receptor polymorphisms and cancer in Caucasian populations: a meta-analysis.

  25540946   Leu72Met408 Polymorphism of the Ghrelin Gene Is Associated With Early Phase of Gastric Emptying in the Patients With Functional Dyspepsia in Japan.

  25868387   The association between rs4684677 T/A polymorphism in preproghrelin gene and predisposition to autoimmune thyroid diseases in children.

  26059200   Genetic variation of the growth hormone secretagogue receptor gene is associated with alcohol use disorders identification test scores and smoking.

  26375586   Ghrelin Gene Variants Influence on Metabolic Syndrome Components in Aged Spanish Population.

  27750262   The obestatin/ghrelin ratio and ghrelin genetics in adult celiac patients before and after a gluten-free diet, in irritable bowel syndrome patients and healthy individuals.

  28146431   Association of plasma ghrelin levels and ghrelin rs4684677 polymorphism with mild cognitive impairment in type 2 diabetic patients.

  28956366   Leu72Met and Other Intronic Polymorphisms in the GHRL and GHSR Genes Are Not Associated with Type 2 Diabetes Mellitus, Insulin Resistance, or Serum Ghrelin Levels in a Saudi Population.