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SNP information rs4343

Normal allele: AA

The GG genotype of the ACE rs4343 polymorphism represents a reliable nutrigenetic marker of adverse response to a diet high in saturated fat.

Polymorphism rs4343 is related to topics like this:

The healthy eating habits of individuals residing in countries surrounding the Mediterranean Sea,...

Research and publications:

  16642441   Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community.

  17173513   No association between variants in the ACE and angiotensin II receptor 1 genes and acute mountain sickness in Nepalese pilgrims to the Janai Purnima Festival at 4380 m.

  17460369   Angiotensin-converting enzyme gene 2350 G/A polymorphism is associated with left ventricular hypertrophy but not essential hypertension.

  18076107   Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis.

  18194558   A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

  18622756   An alternative method for genotyping of the ACE I/D polymorphism.

  18637188   RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population.

  18698231   Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  19105203   An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.

  19108684   ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy.

  19291311   ACE I/D genotype, adiposity, and blood pressure in children.

  20066004   A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.

  20486282   Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20577119   Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study.

  20625269   Amyloid-β-related genes SORL1 and ACE are genetically associated with risk for late-onset Alzheimer disease in the Chinese population.

  20639399   Review: association between angiotensin converting enzyme G2350A polymorphism and hypertension risk: a meta-analysis.

  20682755   A pilot study of gene/gene and gene/environment interactions in Alzheimer disease

  20816195   Analyses of shared genetic factors between asthma and obesity in children.

  21085187   Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP.

  21128019   Genetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies.

  21258267   Angiotensin-converting enzyme tag single nucleotide polymorphisms in patients with intracerebral hemorrhage.

  21444836   Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.

  21709586   Common variants of the ACE gene and aneurysmal subarachnoid hemorrhage in a Danish population: a case-control study.

  21832968   Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of ACE, ABO, and BDKRB2 genes.

  21966275   Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

  22024213   A novel gene-environment interaction involved in endometriosis

  22151803   The insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme gene and cancer risk: a meta-analysis.

  22234866   Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.

  22388798   Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  23065222   Association of angiotensin-converting enzyme gene 2350 G/A polymorphism with diabetic retinopathy in Chinese Han population.

  23497168   Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population.

  23894628   Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.

  24586218   Pleiotropic effect of common variants at ABO Glycosyltranferase locus in 9q32 on plasma levels of pancreatic lipase and angiotensin converting enzyme.

  24625756   Genetic determinants influencing human serum metabolome among African Americans.

  24658007   Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese.

  24722536   Relationship of renin-angiotensin-aldosterone system polymorphisms and phenotypes to mortality in Chinese coronary atherosclerosis patients.

  24959828   Genetic association study with metabolic syndrome and metabolic-related traits in a cross-sectional sample and a 10-year longitudinal sample of chinese elderly population.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  26283679   Correlation between renin-angiotensin system gene polymorphisms and essential hypertension in the Chinese Yi ethnic group.

  26791477   The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.

  26819062   Characterizing redescriptions using persistent homology to isolate genetic pathways contributing to pathogenesis.

  27082637   Genetic Variants of Angiotensin-Converting Enzyme Are Linked to Autism: A Case-Control Study.

  27262302   Influence of ACE gene on differential response to sertraline versus fluoxetine in patients with major depression: a randomized controlled trial.

  27411394   Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus.

  27425626   EDN1 Gene Variant is Associated with Neonatal Persistent Pulmonary Hypertension.

  28096099   High-Saturated-Fat Diet Increases Circulating Angiotensin-Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient-Dependent Increases of Blood Pressure.

  28294743   [The Study of Associations of Polymorphisms of Candidate Gene of Cardiovascular Diseases With Reduction of Glomerular Filtration Rate in Patients With ST Segment Elevation Myocardial Infarction].

  28513230   Association of renin-angiotensin-aldosterone system gene polymorphisms with left ventricular hypertrophy in patients with heart failure with preserved ejection fraction: A case-control study.

  28626926   Angiotensin-converting enzyme gene rs4343 polymorphism increases susceptibility to migraine.

  28835639   Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes.

  28865601   Relationship of the MTHFD1 (rs2236225), eNOS (rs1799983), CBS (rs2850144) and ACE (rs4343) gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects.

  29546999   Association of angiotensin-converting enzyme gene polymorphism with pulse pressure and its interaction with obesity status in Heilongjiang province.

  29627490   Genetically determined enlargement of carotid body evaluated using computed angiotomography.

  30127488   ACE gene rs4343 polymorphism elevates the risk of preeclampsia in pregnant women.

  30387422   [Genetic Polymorphisms Associated with the Onset of Arterial Hypertension in a Portuguese Population].

  30800252   Development of One-Step Tetra-primer ARMS-PCR for Simultaneous Detection of the Angiotensin Converting Enzyme (ACE) I/D and rs4343 Gene Polymorphisms and the Correlation with CAD Patients.

  31195108   Genetic polymorphism of angiotensin converting enzyme and angiotensin II type 1 receptors and their impact on the outcome of acute coronary syndrome.

  31198195   Association Between Polymorphisms in the Angiotensin-Converting Enzyme Gene and Non-Obstructive Azoospermia in the Chinese Han Population from Northeast China.

  31231424   Genetic and Epigenetic Studies in Diabetic Kidney Disease.

  32398726   Genetic Polymorphisms, Mediterranean Diet and Microbiota-Associated Urolithin Metabotypes can Predict Obesity in Childhood-Adolescence.

  32476831   ACE gene variants and sarcoidosis in a Finnish population.

  32591971   Genetically, Dietary Sodium Intake Is Causally Associated with Salt-Sensitive Hypertension Risk in a Community-Based Cohort Study: a Mendelian Randomization Approach.

  33572708   Association of Genetic Variances in ADRB1 and PPARGC1a with Two-Kilometre Running Time-Trial Performance in Australian Football League Players: A Preliminary Study.

  34131278   Genetic polymorphisms associated with obesity in the Arab world: a systematic review.

  34483678   Haematological Indicators of Response to Erythropoietin Therapy in Chronic Renal Failure Patients on Haemodialysis: Impact of Angiotensin-Converting Enzyme rs4343 Gene Polymorphism.

  34489863   ACE Gene Variants Rise the Risk of Severe COVID-19 in Patients With Hypertension, Dyslipidemia or Diabetes: A Spanish Pilot Study.

  35305693   SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease.

  35601073   Differential impact of the angiotensin-converting enzyme-2 (ACE2 rs4343 G>A) and miR-196a2 rs11614913 C>T gene alterations in COVID-19 disease severity and mortality.

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