SNP information rs41423247

Research and publications:

  18952539   No association of glucocorticoid receptor polymorphisms with asthma and response to glucocorticoids.

  20199670   Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study.

  20440229   Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity.

  20547006   FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction.

  20716560   Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.

  21164266   Glucocorticoid resistance.

  21225419   Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.

  21232135   Glucocorticoid receptor gene polymorphism and juvenile idiopathic arthritis.

  21448414   Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

  21803757   Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome.

  21876507   Glucocorticoid receptor polymorphism is associated with lithium response in bipolar patients.

  21967077   A genetic predisposition score for muscular endophenotypes predicts the increase in aerobic power after training: the CAREGENE study.

  22083731   Genetic modulation of neural response during working memory in healthy individuals: interaction of glucocorticoid receptor and dopaminergic genes.

  22410078   Brain activation during fear conditioning in humans depends on genetic variations related to functioning of the hypothalamic-pituitary-adrenal axis: first evidence from two independent subsamples.

  22427805   Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants.

  22445700   The impact of drug metabolizing enzyme polymorphisms on outcomes after antenatal corticosteroid use.

  22507373   Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men.

  22760121   Interaction of the cholinergic system and the hypothalamic-pituitary-adrenal axis as a risk factor for depression: evidence from a genetic association study.

  22781842   Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior.

  22812453   Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder.

  23055001   Genetic evidence for the association of the hypothalamic-pituitary-adrenal (HPA) axis with ADHD and methylphenidate treatment response.

  23213652   Abstracts of the American College of Neuropsychopharmacology (ACNP) 51st Annual Meeting. December 2-6, 2012. Hollywood, Florida, USA.

  23892712   Associations between polymorphisms in the glucocorticoid-receptor gene and cardiovascular risk factors in a Chinese population.

  24166410   HPA axis genetic variation, cortisol and psychosis in major depression.

  24497894   A Conceptual Model of Psychoneurological Symptom Cluster Variation in Women with Breast Cancer: Bringing Nursing Research to Personalized Medicine.

  24741566   Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy.

  25104270   Polymorphisms in NR3C1 gene associated with risk of metabolic syndrome in a Chinese population.

  25113244   The relationship between glucocorticoid receptor polymorphisms, stressful life events, social support, and post-traumatic stress disorder.

  25220664   A common mineralocorticoid receptor polymorphism (I180V) interacts with life events in relation to perfectionism in eating disorders: a pilot study.

  25583614   HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.

  25644744   Single nucleotide polymorphisms in non-coding region of the glucocorticoid receptor gene and prednisone response in childhood acute lymphoblastic leukemia.

  25724472   Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis.

  25741362   Use of pharmacogenomics in pediatric renal transplant recipients.

  25843653   GLCCI1 and Glucocorticoid Receptor Genetic Diversity and Response to Glucocorticoid-Based Treatment of Graft-versus-Host Disease.

  26106668   Can Genetics Predict Response to Complex Behavioral Interventions? Evidence from a Genetic Analysis of the Fast Track Randomized Control Trial.

  26189450   Genetic Moderation of Stress Effects on Corticolimbic Circuitry.

  26518448   Case-control study of glucocorticoid receptor and corticotrophin-releasing hormone receptor gene variants and risk of perinatal depression.

  26595470   Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.

  26821164   Glucocorticoid Receptor (NR3C1) Variants Associate with the Muscle Strength and Size Response to Resistance Training.

  26823689   The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation.

  26873309   Glucocorticoid receptor polymorphisms modulate cardiometabolic risk factors in patients with long-term remission of Cushing's syndrome.

  27003716   Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation.

  27081784   A novel approach to understanding the role of polymorphic forms of the NR3C1 and TGF-β1 genes in the modulation of the expression of IL-5 and IL-15 mRNA in asthmatic inflammation.

  27247801   Single Nucleotide Polymorphisms in Pediatric Idiopathic Nephrotic Syndrome.

  27397864   Glucocorticoid receptor gene modulates severity of depression in women with crack cocaine addiction.

  27400218   Analyses of the role of the glucocorticoid receptor gene polymorphism (rs41423247) as a potential moderator in the association between childhood overweight, psychopathology, and clinical outcomes in Eating Disorders patients: A 6 years follow up

  27401254   Associations between the neuron-specific glucocorticoid receptor (NR3C1) Bcl-1 polymorphisms and suicide in cancer patients within the first year of diagnosis.

  27427275   Association of germline genetic variants in RFC, IL15 and VDR genes with minimal residual disease in pediatric B-cell precursor ALL.

  27428087   Influence of BclI C/G (rs41423247) on hippocampal shape and white matter integrity of the parahippocampal cingulum in major depressive disorder.

  27507764   HPA axis dysregulation, NR3C1 polymorphisms and glucocorticoid receptor isoforms imbalance in metabolic syndrome.

  27509264   Glucocorticoid Receptor Gene Variants and Neonatal Outcome in Very-Low-Birth-Weight Preterm Infants.

  27528460   HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition.

  27688786   Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia.

  28142104   A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.

  28178077   Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock.

  28237884   Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels.

  28262345   Influence of NR3C1 and VDR polymorphisms on stable warfarin dose in patients with mechanical cardiac valves.

  28334414   Association of a Haplotype in the NR3C2 Gene, Encoding the Mineralocorticoid Receptor, With Chronic Central Serous Chorioretinopathy.

  28364727   Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function.

  28641498   Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder.

  29100174   The role of genetic variation in the glucocorticoid receptor (NR3C1) and mineralocorticoid receptor (NR3C2) in the association between cortisol response and cognition under acute stress.

  29526633   Association between allelic variants of the human glucocorticoid receptor gene and autoimmune diseases: A systematic review and meta-analysis.

  29761890   Glucocorticoid receptor gene variants and lower expression of NR3C1 are associated with cocaine use.

  29802709   Association Between NR3C1 Gene Polymorphisms and Toxicity Induced by Glucocorticoids Therapy in Saudi Children with Acute Lymphoblastic Leukemia.

  29879676   Genetic variation in the glucocorticoid receptor and psychopathology after dexamethasone administration in cardiac surgery patients.

  30210047   Pharmacogenomic markers of glucocorticoid response in the initial phase of remission induction therapy in childhood acute lymphoblastic leukemia.

  30647901   Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review.

  30999951   NR3C1 gene polymorphisms are associated with high-altitude pulmonary edema in Han Chinese.

  31022961   FKBP5 rs4713916: A Potential Genetic Predictor of Interindividual Different Response to Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease in a Real-Life Setting.

  31724909   Role of NR3C1 and GAS5 genes polymorphisms in multiple sclerosis.

  31820730   Glucocorticoid receptor polymorphisms in rheumatoid arthritis: results from a single centre.

  32032633   Dual biomarkers long non-coding RNA GAS5 and its target, NR3C1, contribute to acute myeloid leukemia.

  32957930   Genetic risk-factors for anxiety in healthy individuals: polymorphisms in genes important for the HPA axis.

  33019527   The Pathways between Cortisol-Related Regulation Genes and PTSD Psychotherapy.

  33133738   Glucocorticoid Receptor Polymorphisms in Children Undergoing Congenital Heart Surgery with Cardiopulmonary Bypass.

  33562675   The Glucocorticoid Receptor Gene (NR3C1) 9β SNP Is Associated with Posttraumatic Stress Disorder.

  34298075   Glucocorticoid receptor Gene (NR3C1) Polymorphisms and Haplotypes in patients with congenital adrenal hyperplasia.

  34466443   Genetic Variant of Glucocorticoid Receptor Gene at rs41423247 and Its Association with Major Depressive Disorder: A Case-Control Study.

  34634320   The relationship between occupational stress and job burnout in coal miners: Interactions between GCCR and SLC6A4 gene polymorphisms and the environment.

  34831409   NR3C1 Glucocorticoid Receptor Gene Polymorphisms Are Associated with Membranous and IgA Nephropathies.

  35488449   ABCB1 gene polymorphisms impact the effect of high-dose intravenous methylprednisolone therapy on optic neuritis associated with AQP4-IgG-positive neuromyelitis optica spectrum disorder.