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SNP information rs4132601

Normal allele: TT

The IKZF1 rs4132601 polymorphism causes susceptibility to acute lymphoblastic leukaemia.

Polymorphism rs4132601 is related to topics like this:

Cancer of the hematopoietic system


Research and publications:

  19684604   Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.

  20453839   Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk.

  20585100   Genome-wide association studies of cancer.

  20919861   Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence.

  21219822   [Recent progress in genetic variants associated with cancer and their implications in diagnostics development].

  21270240   An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes.

  21307401   What are genome-wide association studies telling us about B-cell tumor development?

  21459794   Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia.

  22367438   Genome-wide two-locus epistasis scans in prostate cancer using two European populations.

  23021489   Candidate gene association study in pediatric acute lymphoblastic leukemia evaluated by Bayesian network based Bayesian multilevel analysis of relevance.

  23382691   Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

  24200646   High-resolution melting analyses for genetic variants in ARID5B and IKZF1 with childhood acute lymphoblastic leukemia susceptibility loci in Taiwan.

  24597983   Polymorphism in IKZF1 gene affects age at onset of childhood acute lymphoblastic leukemia.

  25012940   IKZF1 rs4132601 polymorphism and acute lymphoblastic leukemia susceptibility: a meta-analysis.

  25310577   Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.

  25423013   Contribution of polymorphisms in IKZF1 gene to childhood acute leukemia: a meta-analysis of 33 case-control studies.

  25805752   USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania.

  25806972   ARID5B, IKZF1 and non-genetic factors in the etiology of childhood acute lymphoblastic leukemia: the ESCALE study.

  26437776   A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros.

  26575185   Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27149463   Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility.

  27279837   Analysis of possible genetic risk factors contributing to development of childhood acute lymphoblastic leukaemia in the Latvian population.

  27600067   SNP Array in Hematopoietic Neoplasms: A Review.

  28768142   Contributions of IKZF1, DDC, CDKN2A, CEBPE, and LMO1 Gene Polymorphisms to Acute Lymphoblastic Leukemia in a Yemeni Population.

  28879630   Polymorphism in IKZF1 gene affects clinical outcome in diffuse large B-cell lymphoma.

  28947432   IKZF1 Gene in Childhood B-cell Precursor Acute Lymphoblastic Leukemia: Interplay between Genetic Susceptibility and Somatic Abnormalities.

  30806315   The Genetic Variants of IKZF1 Gene Linked with the Growing Risk of Childhood Acute Lymphoblastic Leukaemia.

  31604453   IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study.

  32769565   IKZF1 rs4132601 and rs11978267 Gene Polymorphisms and Acute Lymphoblastic Leukemia: Relation to Disease Susceptibility and Outcome.

  33452870   High frequency of the risk allele of rs4132601 and rs11978267 from the IKZF1 gene in indigenous Mexican population.

  35932035   Association of IKZF1 and CDKN2A gene polymorphisms with childhood acute lymphoblastic leukemia: a high-resolution melting analysis.

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