SNP information rs4129267

Research and publications:

  17903300   Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project

  17903307   Framingham Heart Study genome-wide association: results for pulmonary function measures.

  18439548   Loci associated with metabolic syndrome pathways, including LEPR, HNF1A, IL6R, and GCKR, are associated with plasma C-reactive protein: the Women's Genome Health Study.

  18439552   Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

  18464913   A genome-wide association study identifies protein quantitative trait loci (pQTLs).

  18852330   Interleukin-6 receptor gene, plasma C-reactive protein, and diabetes risk in women.

  19060910   Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

  19197348   Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae

  19468064   Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

  20031577   New loci, including those associated with Crohn's disease, psoriasis and inflammation, were identified in a genome-wide association study of fibrinogen in 17,686 women: the Women's Genome Health Study.

  20978399   Mendelian randomization: potential use of genetics to enable causal inferences regarding HIV-associated biomarkers and outcomes.

  21300955   Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

  21496483   Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway.

  21523452   Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.

  21647738   Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.

  21907864   Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

  21931794   Common variants in CRP and LEPR influence high sensitivity C-reactive protein levels in North Indians.

  22291609   A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

  22554704   The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.

  22595970   Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

  23090857   Emerging genetics of COPD.

  23111417   Interleukin-6 receptor pathways in abdominal aortic aneurysm.

  23386860   Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes.

  23755072   Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma.

  23886662   A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

  23894628   Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.

  25551457   No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

  27327646   Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

  28686695   Coronary artery disease-associated genetic variants and biomarkers of inflammation.

  29200018   The Diagnostic and Prognostic Role of Interleukin 12B and Interleukin 6R Gene Polymorphism in Patients With Ankylosing Spondylitis.

  29513361   A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.

  30090940   Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study.

  32292581   Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis.

  32769481   Inflammatory Genotype Moderates the Association Between Anxiety and Systemic Inflammation in Adults at Risk for Cardiovascular Disease.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34025845   Serum anti-inflammatory and inflammatory markers have no causal impact on telomere length: a Mendelian randomization study.

  35330392   Polymorphisms and Gene-Gene Interaction in AGER/IL6 Pathway Might Be Associated with Diabetic Ischemic Heart Disease.

  35493452   Cumulative Evidence for Associations Between Genetic Variants in Interleukin 6 Receptor Gene and Human Diseases and Phenotypes.