SNP information rs3789243

Research and publications:

  15197162   Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene.

  16434479   ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.

  17828778   Role of the PXR gene locus in inflammatory bowel diseases.

  18424454   ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence.

  18819034   Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population.

  19250544   The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study.

  19450124   Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese.

  19685447   Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis.

  19930591   Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.

  19934400   Genetic predictors of interindividual variability in hepatic CYP3A4 expression.

  20836841   Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes.

  21333900   The role of genetics in IBS

  21530324   Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.

  21686133   Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome.

  21712189   Analysis of pharmacogenetic traits in two distinct South African populations.

  21738081   PharmGKB summary: carbamazepine pathway.

  22396794   A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer.

  23050008   Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population.

  23279665   ABCB1/MDR1 gene polymorphism and colorectal cancer risk: a meta-analysis of case-control studies.

  23977225   Low ABCB1 gene expression is an early event in colorectal carcinogenesis.

  24889212   Systematic review: interactions between aspirin, and other nonsteroidal anti-inflammatory drugs, and polymorphisms in relation to colorectal cancer.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25133031   Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature.

  25355168   Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms.

  25491747   Interactions between meat intake and genetic variation in relation to colorectal cancer.

  27427275   Association of germline genetic variants in RFC, IL15 and VDR genes with minimal residual disease in pediatric B-cell precursor ALL.

  32243098   Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.