Upload the DNA data file of the test

23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage

and get an enhanced
personalized health report
free without registration

Files accepted .txt, .csv, .zip, .csv.gz

File data is not stored on the server

SNP information rs2745557

RS2745557

Normal allele: GG

Also known as cyclooxygenase-2 (Cox-2), is overexpressed (p<0.01) in autism spectrum disorders.

Polymorphism rs2745557 is related to topics like this:

DNA test for autism

We recommend that anyone who has been diagnosed with autism undergo genetic testing. Unfortunately,...


Research and publications:

  17609663   COX2 genetic variation, NSAIDs, and advanced prostate cancer risk.

  18038187   Joint effect between regular use of non-steroidal anti-inflammatory drugs, variants in inflammatory genes and risk of lymphoma.

  18085997   Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

  18579107   Association between PTGS2 polymorphism and autism spectrum disorders in Korean trios.

  18682823   Canadian Urological Association, 63rd Annual Meeting, Edmonton, AB, June 22-25, 2008.

  18768181   Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.

  19318492   Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk.

  19437564   No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk.

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19560328   No association between the PPARG gene and schizophrenia in a British population.

  19755647   Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial.

  19776642   Omega-3 fatty acids, genetic variants in COX-2 and prostate cancer.

  19820421   The effect of genetic polymorphisms of cyclooxygenase 2 on acute pancreatitis in Turkey.

  19965896   PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3)

  20034614   Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels

  20621252   The genetics of vascular complications in diabetes mellitus.

  20676755   Genetic variants in COX-2, non-steroidal anti-inflammatory drugs, and breast cancer risk: the Western New York Exposures and Breast Cancer (WEB) Study.

  20688905   Use of aspirin and other nonsteroidal antiinflammatory medications in relation to prostate cancer risk.

  21063235   PharmGKB summary: very important pharmacogene information for PTGS2.

  21430300   Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.

  21532843   Interaction between use of non-steroidal anti-inflammatory drugs and selected genetic polymorphisms in ovarian cancer risk.

  21705955   Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility.

  22376259   Linkage disequilibrium and haplotype analysis of COX-2 and risk of colorectal adenoma development.

  22435969   Association between COX-2 rs2745557 polymorphism and prostate cancer risk: a systematic review and meta-analysis.

  22551325   No association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study.

  22824134   Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients.

  23272139   Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.

  25368279   Evaluation of the contribution of cyclooxygenase 2 genotypes to breast cancer in Taiwan.

  26920155   Cyclooxygenase 2 (rs2745557) Polymorphism and the Susceptibility to Benign Prostate Hyperplasia and Prostate Cancer in Egyptians.

  26967244   Systematic meta-analyses of gene-specific genetic association studies in prostate cancer.

  27647999   Prognostic Value of Prostaglandin-endoperoxide Synthase 2 Polymorphisms in Prostate Cancer Recurrence after Radical Prostatectomy.

  32100450   Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility.

  33545665   Polymorphisms rs2745557 in PTGS2 and rs2075797 in PTGER2 are associated with the risk of chronic obstructive pulmonary disease development in a Tunisian cohort.

  33565113   Connection of COX-2 variants to ankylosing spondylitis susceptibility.

  35430434   Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case-control study in China.

Gene for lactose intolerance

Lactose intolerance is a condition characterized by difficulty digesting lactose, a sugar present...

CCNB1 cyclin B1

Cyclin B1 serves as a regulatory protein pivotal in the process of mitosis. It forms complexes with...

DNA methylation genes

The Genetic Methylation Check examines your DNA to offer insights into your unique methylation...

en
|
de
|
fr
|
es
|
it
|
ua
|
ru

Support