SNP information rs2229765

Research and publications:

  12843179   Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.

  18477064   Insulin-like growth factor-1 receptor polymorphism and ischemic stroke: a case-control study in Chinese population.

  19124506   Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.

  19124510   Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma

  19460140   A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study.

  19877134   Sequence variation in IGF1R is associated with differences in insulin levels in nondiabetic Old Order Amish.

  20302654   Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.

  20569235   HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

  20580999   Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps.

  20625407   A comprehensive in silico analysis of the functional and structural impact of SNPs in the IGF1R gene.

  20935157   Germline polymorphisms in genes involved in the IGF1 pathway predict efficacy of cetuximab in wild-type KRAS mCRC patients.

  21047277   Polymorphisms of insulin-like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) contribute to pathologic progression in childhood IgA nephropathy.

  21304894   Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis.

  21791631   Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

  22115178   Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva--TRELONG).

  22156437   Discovery of functional gene variants associated with human longevity: opportunities and challenges.

  22303384   Whole genome sequences of a male and female supercentenarian, ages greater than 114 years.

  22909219   Polymorphism of IGF1R is associated with papillary thyroid carcinoma in a Korean population.

  24895547   Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions.

  25189651   Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development.

  26535220   Association between exonic polymorphism (rs629849, Gly1619Arg) of IGF2R gene and obesity in Korean population.

  27144430   Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX.

  27213344   The Clinical Significance of the Insulin-Like Growth Factor-1 Receptor Polymorphism in Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation.

  27376028   Polymorphisms of Insulin-Like Growth Factor 1 Pathway Genes and Breast Cancer Risk.

  27405474   Insulin-like growth factor-1 signaling in renal cell carcinoma.

  28050343   Brain insulin resistance deteriorates cognition by altering the topological features of brain networks.

  28119888   Association study between growth hormone receptor (GHR ) gene polymorphisms and obesity in Korean population.

  28213921   Maternal IGF1 and IGF1R polymorphisms and the risk of spontaneous preterm birth.

  29126188   Insulin-Like Growth Factor-1 and Receptor Contribute Genetic Susceptibility to Hypertension in a Han Chinese Population.

  32150843   A Possible Link of Genetic Variations in ER/IGF1R Pathway and Risk of Melanoma.

  26445852   Genetic biomarkers of susceptibility and progression of Barrett's esophagus to dysplasia and cancer: a systematic review and meta-analysis.

  27536357   Genetic predisposition to Barrett's esophagus: lessons from early research.

  34501407   Insulin-like growth factor-1 receptor 3179G/A polymorphism: a novel susceptibility factor in anti-Ro/SSA-positive patients with Sjögren's syndrome: potential clinical and pathogenetic implications.