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SNP information rs1887922

RS1887922

Normal allele: TT

Polymorphisms in the insulin-degrading enzyme (IDE) gene determine insulin metabolism and the risk of developing type 2 diabetes. It also affects a person's life expectancy.

Polymorphism rs1887922 is related to topics like this:

INSR Gene Insulin Receptor

The gene known as INSR directs the production of insulin receptors - proteins present in various...

Research and publications:

  12765971   Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

  15718037   IDE sequence variants are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.

  16385451   A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

  17953957   Association of genetic variants of insulin degrading enzyme with metabolic features in women with polycystic ovary syndrome.

  18448515   Evidence that the gene encoding insulin degrading enzyme influences human lifespan

  19809796   Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes.

  22107728   Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene.

  22502914   Association between two single nucleotide polymorphisms in the insulin-degrading enzyme gene and Alzheimer's disease in the Chinese Han population.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  25414272   Association between polymorphisms of the insulin-degrading enzyme gene and late-onset Alzheimer disease.

  28050343   Brain insulin resistance deteriorates cognition by altering the topological features of brain networks.

  35546756   Association of polymorphisms of the BIN1, CLU and IDE genes with susceptibility to Alzheimer's disease: meta-analysis data.

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