Normal allele: GG
A polymorphism in the DRD2 gene for the dopamine D2 receptor increases 1.4-fold the risk of schizophrenia in the heterozygous GC genotype.
Polymorphism rs1801028 is related to topics like this:
Research and publications:
18154681 A lesson not learned: allele misassignment.
18715757 Genetic associations with schizophrenia: meta-analyses of 12 candidate genes
19512960 Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.
19913597 An association study of DRD2 gene polymorphisms with schizophrenia in a Chinese Han population.
20736885 PharmGKB summary: dopamine receptor D2.
21162693 Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.
21172166 Pharmacogenetics of antidepressant response.
21687501 Pharmacogenetics of antidepressants.
21728034 Methamphetamine-associated psychosis.
21981786 The genetic validation of heterogeneity in schizophrenia.
22650965 Paradox of schizophrenia genetics: is a paradigm shift occurring?
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
25711927 DRD2 Ser311Cys polymorphism and risk of schizophrenia.
26730182 Association between GRK4 and DRD1 gene polymorphisms and hypertension: a meta-analysis.
27757066 Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.
30093869 Biological Predictors of Clozapine Response: A Systematic Review.
30607769 Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.
34824904 Genetic diversity of "highly important pharmacogenes" in two South Asian populations.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.