SNP information rs1800795

Research and publications:

  15113403   Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  15820616   IL-6 gene variation is not associated with increased serum levels of IL-6, muscle, weakness, or frailty in older women

  16046815   Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16544245   Host immunogenetics and control of human herpesvirus-8 infection

  16617143   Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

  16644865   Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis

  16759385   Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  16820586   Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

  16842617   Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review

  16846490   Lemierre's syndrome and genetic polymorphisms: case report

  17003362   IL6 gene promoter polymorphism and type 2 diabetes: pooled analysis of individual participant data from 21 studies

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17416766   IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States

  17594514   Active and passive smoking, IL6, ESR1, and breast cancer risk

  17623760   Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individuals

  17665434   Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status

  17694420   IL6 genotypes and colon and rectal cancer

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  17847004   Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance

  17903293   Genome-wide association with select biomarker traits in the Framingham Heart Study

  17916900   Single-nucleotide polymorphisms in selected cytokine genes and risk of adult glioma

  17996468   Polymorphisms of the interleukin-6 gene promoter and abdominal aortic aneurysm

  18041006   Association of TGF-beta1 codon 25 (G915C) polymorphism with hepatitis C virus infection

  18045485   The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

  18216863   Genetic determinants of basal C-reactive protein expression in Filipino systemic lupus erythematosus families

  18239642   Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk

  18257935   Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis

  18276608   Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth

  18307517   Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans

  18321738   Is the interleukin-6 haplotype a prognostic factor for sciatica?

  18420533   The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs

  18436879   Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study

  18449426   Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease--the Indian Atherosclerosis Research Study

  18458677   Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment

  18496509   An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients

  18500540   Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach

  18505952   Genetic susceptibility to cancer: the role of polymorphisms in candidate genes

  18603647   Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18687755   Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population

  18689695   Predicting diabetes: clinical, biological, and genetic approaches: data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR)

  18752089   Pooled analysis of individual participant data from 17 studies on the association of the IL6 -174Gu003eC variant with circulating glucose levels, interleukin-6 levels, and body mass index.

  18779388   Assessing the potential for excess of statistically significant results in published genetic association studies: Application to Alzheimer's disease.

  18781131   Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma

  18787421   Genetic contributions to disparities in preterm birth

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  18992148   Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study

  18992263   Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways

  19034965   Genetic determination of irritable bowel syndrome

  19035456   Adipokine genes and prostate cancer risk

  19056105   DNA variants, plasma levels and variability of interleukin-6 in myocardial infarction survivors: results from the AIRGENE study

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19106168   Transforming growth factor-beta1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis

  19124510   Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19131814   Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study

  19140096   The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications

  19147066   Genomic and proteomic analysis of allogeneic hematopoietic cell transplant outcome. Seeking greater understanding the pathogenesis of GVHD and mortality

  19249341   Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19267250   C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older

  19272152   IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study

  19280716   The IL6-174G/C polymorphism is associated with celiac disease susceptibility in girls

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19347053   Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19359268   Associations of IL6 polymorphisms with lung function decline and COPD

  19377912   Interleukin-6 plasma level increases with age in an Italian elderly population ("The Treviso Longeva"-Trelong-study) with a sex-specific contribution of rs1800795 polymorphism

  19387461   Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection

  19401444   Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism

  19435922   Host genetic variants in the interleukin-6 promoter predict poor outcome in patients with estrogen receptor-positive, node-positive breast cancer

  19452524   Tumor markers and rectal cancer: support for an inflammation-related pathway

  19478423   Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels

  19501493   A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study

  19503017   Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19542902   The -174GG interleukin-6 genotype is protective from retinopathy and nephropathy in juvenile onset type 1 diabetes mellitus

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  19592000   Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey

  19671870   Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor)

  19698145   Replication by the Epistasis Project of the interaction between the IL-6 and IL-10 genes in Alzheimer's disease risk.

  19729864   Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study

  19734419   A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support

  19750100   Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  19833146   Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain

  19853505   The -174 G/C polymorphism of the IL6 gene is associated with elite power performance

  19876004   Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study

  19912668   Design and evaluation of a treatment programme for Spanish adolescents with overweight and obesity. The EVASYON Study

  19942621   An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

  19965896   PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3)

  20012999   The cancer anorexia/weight loss syndrome: exploring associations with single nucleotide polymorphisms (SNPs) of inflammatory cytokines in patients with non-small cell lung cancer

  20031584   Genetics of atherothrombotic and lacunar stroke

  20034614   Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels

  20043205   Lack of an association between a functional polymorphism in the interleukin-6 gene promoter and breast cancer risk: a meta-analysis involving 25,703 subjects

  20044998   Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis