SNP information rs1800532

Research and publications:

  15206000   Transmission disequilibrium studies in children and adolescents with obsessive-compulsive disorders pertaining to polymorphisms of genes of the serotonergic pathway.

  15799788   Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan.

  17483451   Gene-gene interaction associated with neural reward sensitivity

  17521439   Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.

  18782386   Tryptophan hydroxylase 2 gene and alcohol use among college students.

  19258022   Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network.

  19590397   5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

  19911060   Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20043001   Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.

  20144688   Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population.

  20159343   The genetics of major depression: moving beyond the monoamine hypothesis.

  20201854   Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

  20421849   Habituation in prepulse inhibition is affected by a polymorphism on the NMDA receptor 2B subunit gene (GRIN2B).

  20580984   Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.

  20945066   TPH1 is associated with major depressive disorder but not with SSRI/SNRI response in Taiwanese patients.

  21073637   Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.

  21172166   Pharmacogenetics of antidepressant response.

  21333900   The role of genetics in IBS

  21601290   Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies.

  21687501   Pharmacogenetics of antidepressants.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21981786   The genetic validation of heterogeneity in schizophrenia.

  21989108   Interaction between tryptophan hydroxylase I polymorphisms and childhood abuse is associated with increased risk for borderline personality disorder in adulthood.

  22224195   Epigenetics in Developmental Disorder: ADHD and Endophenotypes.

  22594806   Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia.

  22650965   Paradox of schizophrenia genetics: is a paradigm shift occurring?

  22695700   The genetic epidemiology of idiopathic scoliosis

  23032942   The association of attempted suicide with genetic variants in the SLC6A4 and TPH genes depends on the definition of suicidal behavior: a systematic review and meta-analysis.

  23172723   TPH gene polymorphisms are associated with disease perception and quality of life in women with irritable bowel syndrome.

  23221997   TPH1, MAOA, serotonin receptor 2A and 2C genes in citalopram response: possible effect in melancholic and psychotic depression.

  23313272   An association study of suicide and candidate genes in the serotonergic system.

  23499153   Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  23810197   Genetic modulation of borderline personality disorder: systematic review and meta-analysis.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  25005534   Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

  25419635   Association between the TPH1 A218C polymorphism and antidepressant response: evidence from an updated ethnicity, antidepressant-specific, and ethnicity-antidepressant interaction meta-analysis.

  26390831   Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways.

  27037949   Tryptophan Hydroxylase 1 Variant rs1800532 is Associated with Suicide Attempt in Serbian Psychiatric Patients but does not Moderate the Effect of Recent Stressful Life Events.

  27045756   TPH1 and 5-HTTLPR Genes Specifically Interact in Opiate Dependence but Not in Alcohol Dependence.

  27375535   Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review.

  27521242   TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs.

  27573591   Personality traits as an endophenotype in genetic studies on suicidality in bipolar disorder.

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  28822116   Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

  28951738   Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders.

  29314569   Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.

  29358097   The effect of 5-HTTLPR and a serotonergic multi-marker score on amygdala, prefrontal and anterior cingulate cortex reactivity and habituation in a large, healthy fMRI cohort.

  29684863   Psychological and genetic risk factors associated with suicidal behavior in Korean patients with mood disorders.

  30602107   Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts.

  30789538   Association of polymorphisms in HTR2A, TPH1, and TPH2 genes with attempted suicide in rural China.

  31721892   Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial.

  31817010   Variation of Genes Encoding Tryptophan Catabolites Pathway Enzymes in Stroke.

  32576619   Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.

  33986613   MAOB rs3027452 Modifies Mood Improvement After Tryptophan Supplementation.

  34082673   Suicide and Genetic Biomarkers: Toward Personalized Tailored-treatment with Lithium and Clozapine.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

  35928776   Association between TPH1 polymorphisms and the risk of suicide behavior: An updated meta-analysis of 18,398 individuals.