SNP information rs1799750

Research and publications:

  15817713   Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations

  16311244   Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.

  16356191   Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study.

  17054776   The genetics of chronic obstructive pulmonary disease

  17363767   Genetic determinants of emphysema distribution in the national emphysema treatment trial.

  18787421   Genetic contributions to disparities in preterm birth

  18787887   Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures

  18802702   Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms).

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  19318431   No association between matrix metalloproteinase-1 or matrix metalloproteinase-3 polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer Study.

  19321798   Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.

  19379518   Development of a fingerprinting panel using medically relevant polymorphisms.

  19406964   Association of genetic variants with chronic kidney disease in Japanese individuals.

  19435861   No association between matrix metalloproteinase (MMP)-1, MMP-3, and MMP-7 SNPs and endometrial cancer risk.

  19508478   Polymorphism of matrix metalloproteinase genes (MMP1 and MMP3) in patients with varicose veins.

  19551141   Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinoma.

  19664242   Functional polymorphisms in matrix metalloproteinases -1, -3, -9 and -12 in relation to cervical artery dissection.

  19681861   Forty-two novel COL7A1 mutations and the role of a frequent single nucleotide polymorphism in the MMP1 promoter in modulation of disease severity in a large European dystrophic epidermolysis bullosa cohort.

  19951401   Chronic obstructive pulmonary disease: towards pharmacogenetics

  20038976   Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.

  20078883   Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.

  20111728   Joint effect of MCP-1 genotype GG and MMP-1 genotype 2G/2G increases the likelihood of developing pulmonary tuberculosis in BCG-vaccinated individuals.

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20655738   Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.

  20808730   Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.

  20827277   Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease.

  21161369   Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis.

  21244504   Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration.

  21410539   Matrix metalloproteinase genes on chromosome 11q22 and the risk of anterior cruciate ligament (ACL) rupture.

  21524282   Genetic variation in TIMP1 but not MMPs predict excess FEV1 decline in two general population-based cohorts.

  22024213   A novel gene-environment interaction involved in endometriosis

  22174852   Comparing methods for mapping cis acting polymorphisms using allelic expression ratios.

  22300735   Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factors.

  22348060   Association between polymorphisms in the promoter regions of matrix metalloproteinases (MMPs) and risk of cancer metastasis: a meta-analysis.

  22388798   Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.

  22776467   Age at onset of rheumatoid arthritis: association with polymorphisms in the vascular endothelial growth factor A(VEGFA) gene and an intergenic locus between matrix metalloproteinase (MMP) 1 and 3 genes.

  22992122   Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study.

  22993337   Association of matrix metalloproteinase-1 polymorphisms with risk of COPD and lung cancer and survival in lung cancer.

  23274712   Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.

  23370084   The MMP1 rs1799750 2G allele is associated with increased low back pain, sciatica, and disability after lumbar disk herniation.

  23644943   Influence of matrix metalloproteinase-1 gene -1607 (1G/2G) (rs1799750) promoter polymorphism on circulating levels of MMP-1 in chronic pancreatitis.

  23813847   The association of genetic variants of matrix metalloproteinases with abdominal aortic aneurysm: a systematic review and meta-analysis.

  23819551   Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility.

  23820649   Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

  23941979   Association of genetic polymorphisms with histological grading of necroinflammation, staging of fibrosis, and liver function in Mexicans with chronic hepatitis C virus infection.

  23946168   Translational genomics of acquired laryngotracheal stenosis.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24134675   Matrix metalloproteinase-1 promoter -1607 1G/2G polymorphism and chronic periodontitis susceptibility: a meta-analysis and systematic review.

  24635493   Functional polymorphisms in the matrix metalloproteinase genes and their association with bladder cancer risk and recurrence: a mini-review.

  24834361   Update on abdominal aortic aneurysm research: from clinical to genetic studies.

  24838892   Association of MMP-1 -1607 1G/2G (rs1799750) polymorphism with primary knee osteoarthritis in the Greek population.

  24995609   MMP-1 promoter genotype and haplotype association with posterior tibial tendinopathy.

  25111588   Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women.

  25148204   The contribution of the genetic variations of the matrix metalloproteinase-1 gene to the genetic susceptibility of gastric cancer.

  25372932   Genetic polymorphism of matrix metalloproteinase-1 and coronary artery disease susceptibility: a case-control study in a Han Chinese population.

  25599395   MMP-1 and -3 promoter variants are indicative of a common susceptibility for skin and lung aging: results from a cohort of elderly women (SALIA).

  25950130   Analysis of the Association of Matrix Metalloproteinase-1 Gene Promoter (rs1799750) Polymorphism and Risk of Ovarian Cancer.

  26445852   Genetic biomarkers of susceptibility and progression of Barrett's esophagus to dysplasia and cancer: a systematic review and meta-analysis.

  26521080   Matrix metalloproteinase genes on chromosome 11q22 and risk of carpal tunnel syndrome.

  26528997   Association of MMP1, MMP2 and MMP3 gene polymorphisms with pneumoconiosis of coal industry workers in the Chinese Han population.

  26587841   Candidate Gene Analysis of Mortality in Dialysis Patients.

  27428613   Matrix metalloproteinase-1 rs1799750 polymorphism and glaucoma: A meta-analysis.

  27536357   Genetic predisposition to Barrett's esophagus: lessons from early research.

  27556208   MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements.

  27620811   Associations between various possible promoter polymorphisms of MMPs genes and endometriosis risk: a meta-analysis.

  27886420   Posterior tibial tendinopathy associated with matrix metalloproteinase 13 promoter genotype and haplotype.

  27964712   Genes associated with persistent lumbar radicular pain; a systematic review.

  28002595   Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis.

  28612708   Contribution of matrix metalloproteinases-1 genotypes to gastric cancer susceptibility in Taiwan.

  28944430   Polymorphism of Matrix Metalloproteinases Genes MMP1, MMP2, MMP3, and MMP7 and the Risk of Varicose Veins of Lower Extremities.

  28949773   Gene-Gene Interactions Between Glutathione S-Transferase M1 and Matrix Metalloproteinases 1, 9, and 12 in Chronic Obstructive Pulmonary Disease in Serbians.

  28957437   Association between matrix metalloproteinases polymorphisms and ovarian cancer risk: A meta-analysis and systematic review.

  29044936   MMP1 and MMP3 gene polymorphisms in patients with acute coronary syndromes.

  29096757   Matrix metalloproteinase-1 (MMP-1) rs1799750 polymorphism is associated with nasopharyngeal carcinoma (NPC) risk.

  29164621   Determining Candidate Single Nucleotide Polymorphisms in Acquired Laryngotracheal Stenosis.

  29277780   The Contribution of Matrix Metalloproteinase-1 Promoter Genotypes in Taiwan Lung Cancer Risk.

  29291905   Multiple sites of vascular dilation or aneurysmal disease and matrix metalloproteinase genetic variants in patients with abdominal aortic aneurysm.

  29369548   [Association of gene polymorphisms of matrix metalloproteinases with reproductive losses in the first trimester of pregnancy].

  29458338   Association of matrix metalloprotease 1, 3, and 12 polymorphisms with rheumatic heart disease in a Chinese Han population.

  29476163   Genetic predictors of systemic sclerosis-associated interstitial lung disease: a review of recent literature.

  29947568   The association of matrix metalloproteinases polymorphisms and interleukins in advanced age-related macular degeneration.

  30177524   The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk.

  30328228   Matrix metalloproteinases gene polymorphism haplotype is a risk factor to implant loss: A case-control study.

  30464622   Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review.

  30691874   Effects of MMP-1 1G/2G polymorphism on osteoarthritis: A meta-analysis study.

  30715578   Genetic association in female stress urinary incontinence based on proteomic findings: a case-control study.

  30793520   Cumulative evidence for association between genetic polymorphisms and esophageal cancer susceptibility: A review with evidence from meta-analysis and genome-wide association studies.

  30886066   Lack of association between matrix metalloproteinase-1 gene rs1799750 polymorphism and osteoarthritis susceptibility: a meta-analysis.

  30901387   Association of Gene Polymorphisms With Primary Open Angle Glaucoma: A Systematic Review and Meta-Analysis.

  31056794   Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease.

  31356534   Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.

  31441739   [Study of associations of polymorphism of matrix metalloproteinases genes with the development of arterial hypertension in men].

  31516756   Genetic polymorphisms and gastric cancer risk: a comprehensive review synopsis from meta-analysis and genome-wide association studies.

  31652448   Role of matrix metalloproteases 1/3 gene polymorphisms in patients with rotator cuff tear.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  32127761   Two novel SNPs in genes involved in immune response and their association with mandibular residual ridge resorption.

  32323264   Association of the polymorphisms of the genes APOC3 (rs2854116), ESR2 (rs3020450), HFE (rs1799945), MMP1 (rs1799750) and PPARG (rs1801282) with lipodystrophy in people living with HIV on antiretroviral therapy: a systematic review.

  32596320   Association between the MMP-1-1607 1G/2G Polymorphism and Osteoarthritis Risk: A Systematic Review and Meta-Analysis.

  32650441   Matrix Metalloproteinase Genes (MMP1, MMP10, MMP12) on Chromosome 11q22 and the Risk of Non-Contact Anterior Cruciate Ligament Ruptures.