SNP information rs11615

Research and publications:

  15213713   A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer.

  15734977   Gene-smoking interaction associations for the ERCC1 polymorphisms in the risk of lung cancer.

  17299578   Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.

  18332046   A distinct ERCC1 haplotype is associated with mRNA expression levels in prostate cancer patients.

  18347182   Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

  18544627   Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk.

  18635523   Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: a genotype-phenotype correlation analysis.

  18990748   International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.

  19361884   Effects of excision repair cross-complementation group 1 (ERCC1) single nucleotide polymorphisms on the prognosis of non-small cell lung cancer patients.

  19362955   DNA repair gene polymorphisms predict favorable clinical outcome in advanced non-small-cell lung cancer.

  19442035   Pharmacogenomics of platinum-based chemotherapy in NSCLC.

  19536092   Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.

  19620936   Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes.

  19786980   Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients.

  20003391   ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.

  20003463   Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma.

  20847277   Genotyping of DNA samples isolated from formalin-fixed paraffin-embedded tissues using preamplification.

  20935060   Genetic modifiers of carcinogen DNA adducts in target lung and peripheral blood mononuclear cells

  20981448   A novel survival multifactor dimensionality reduction method for detecting gene-gene interactions with application to bladder cancer prognosis.

  21057378   Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy.

  21075476   No evidence of an association of ERCC1 and ERCC2 polymorphisms with clinical outcomes of platinum-based chemotherapies in non-small cell lung cancer: a meta-analysis.

  21262916   Thymidylate synthase and excision repair cross-complementing group-1 as predictors of responsiveness in mesothelioma patients treated with pemetrexed/carboplatin.

  21278243   ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.

  21315089   The ERCC1 N118N polymorphism does not change cellular ERCC1 protein expression or platinum sensitivity.

  21364592   CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patients.

  21487324   Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer.

  21504893   DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas.

  21553053   The determination of relationship between "excision repair cross-complementing group 1" (ERCC1) gene T19007C and C8092A single nucleotide polymorphisms and clinicopathological parameters in non-small cell lung cancer.

  21601580   HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population.

  21686133   Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome.

  21739480   Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.

  21750170   Polymorphisms in nucleotide excision repair genes and endometrial cancer risk.

  21826087   Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy.

  21902499   Pharmacogenetic analyses of cisplatin-induced nephrotoxicity indicate a renoprotective effect of ERCC1 polymorphisms.

  21956434   Neoadjuvant radiochemotherapy in adenocarcinoma of the esophagus: ERCC1 gene polymorphisms for prediction of response and prognosis.

  21989229   DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a case-control study.

  22002622   Nucleotide excision repair gene ERCC1 polymorphisms contribute to cancer susceptibility: a meta-analysis.

  22026922   Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy.

  22188361   Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins.

  22201261   ERCC1 polymorphisms and risk of adult glioma in a Chinese population: a hospital-based case-control study.

  22300735   Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factors.

  22329723   Association between polymorphisms of ERCC1 and survival in epithelial ovarian cancer patients with chemotherapy.

  22335888   A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population.

  22493747   Germ line variation in nucleotide excision repair genes and lung cancer risk in smokers.

  22740911   Single nucleotide polymorphisms in DNA repair genes and risk of cervical cancer: A case-control study.

  22761669   Meta-analysis on pharmacogenetics of platinum-based chemotherapy in non small cell lung cancer (NSCLC) patients.

  22821389   Polymorphisms of ERCC1 genotype associated with response to imatinib therapy in chronic phase chronic myeloid leukemia.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23147699   Association of genetic polymorphisms in ERCC1 and ERCC2/XPD with risk of chronic benzene poisoning in a Chinese occupational population.

  23166636   Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population.

  23175176   Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.

  23180017   PPP1R13L variant associated with prognosis for patients with rectal cancer.

  23203453   Excision repair of BPDE-adducts in human lymphocytes: diminished capacity associated with ERCC1 C8092A (rs3212986) polymorphism.

  23226053   ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer.

  23680703   A genetic variant in ERCC2 is associated with gastric cancer prognosis in a Chinese population.

  23684781   Phase II study of satraplatin and prednisone in patients with metastatic castration-resistant prostate cancer: a pharmacogenetic assessment of outcome and toxicity.

  23720673   Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.

  23909490   Polymorphisms in the ERCC1 and XPF genes and risk of breast cancer in a Chinese population.

  23962907   ERCC1 C8092A (rs3212986) polymorphism as a predictive marker in esophageal cancer patients treated with cisplatin/5-FU-based neoadjuvant therapy.

  24103542   High-throughput genotyping system as a robust and useful tool in oncology: experience from a single institution.

  24325908   Analysis of DNA repair gene polymorphisms in glioblastoma.

  24499239   Predicting the outcome of platinum-based chemotherapies in epithelial ovarian cancer using the 8092C/A polymorphism of ERCC1: a meta-analysis.

  24563277   Association of single nucleotide polymorphisms of nucleotide excision repair genes with laryngeal cancer risk and interaction with cigarette smoking and alcohol drinking.

  24582975   Laryngeal cancer risk and common single nucleotide polymorphisms in nucleotide excision repair pathway genes ERCC1, ERCC2, ERCC3, ERCC4, ERCC5 and XPA.

  24793015   Association of DNA repair gene polymorphisms with response to chemotherapy and prognosis of gastric cancer in a Chinese population.

  24841208   Association studies of ERCC1 polymorphisms with lung cancer susceptibility: a systematic review and meta-analysis.

  24847383   ERCC1, XRCC1 and GSTP1 Single Nucleotide Polymorphisms and Survival of Patients with Colon Cancer Receiving Oxaliplatin-Based Adjuvant Chemotherapy.

  24859833   Polymorphisms in ERCC1 gene could predict clinical outcome of platinum-based chemotherapy for non-small cell lung cancer patients.

  24861646   Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use.

  24933103   Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer.

  24939416   CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25026457   EGFR ligands and DNA repair genes: genomic predictors of complete response after capecitabine-based chemoradiotherapy in locally advanced rectal cancer.

  25069034   Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.

  25110414   Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years.

  25132748   FOLFOX/FOLFIRI pharmacogenetics: the call for a personalized approach in colorectal cancer therapy.

  25214541   A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.

  25222248   Association of DNA repair gene polymorphisms with response to chemotherapy and prognosis of gastric cancer.

  25232828   Thymidylate synthase genotype-directed chemotherapy for patients with gastric and gastroesophageal junction cancers.

  25340731   Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer.

  25366790   Effect of ERCC1 polymorphism on the response to chemotherapy and clinical outcome of non-small cell lung cancer.

  25452763   Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?

  25542228   Genetic polymorphisms of DNA repair pathways influence the response to chemotherapy and overall survival of gastric cancer.

  25746798   Technical reproducibility of single-nucleotide and size-based DNA biomarker assessment using DNA extracted from formalin-fixed, paraffin-embedded tissues.

  25789018   Analysis of ERCC1 and ERCC2 gene variants in osteosarcoma, colorectal and breast cancer.

  25881102   Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer.

  25961110   DNA repair genes XRCC1 and ERCC1 polymorphisms and the risk of sporadic breast cancer in Han women in the Gansu Province of China.

  26001533   Polymorphisms in ERCC1 and ERCC2/XPD genes and carcinogen DNA adducts in human lung.

  26022132   Association of ERCC1 polymorphisms (rs3212986 and rs11615) with the risk of head and neck carcinomas based on case-control studies.

  26253951   Use a survival model to correlate single-nucleotide polymorphisms of DNA repair genes with radiation dose-response in patients with non-small cell lung cancer.

  26254278   Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy.

  26264164   A Comprehensive Analysis of Influence ERCC Polymorphisms Confer on the Development of Brain Tumors.

  26339355   Genetic polymorphisms in nucleotide excision repair pathway influences response to chemotherapy and overall survival in osteosarcoma.

  26345951   Association between ERCC1 and ERCC2 gene polymorphisms and chemotherapy response and overall survival in osteosarcoma.

  26400354   Investigation of ERCC1 and ERCC2 gene polymorphisms and response to chemotherapy and overall survival in osteosarcoma.

  26426637   Predictive Value of Ercc1 and Xpd Polymorphisms for Clinical Outcomes of Patients Receiving Neoadjuvant Therapy: A Prisma-Compliant Meta-Analysis.

  26436406   Genetic variability of genes involved in DNA repair influence treatment outcome in osteosarcoma.

  26475344   CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer.

  26681190   Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population.

  26751466   Association between UGT1A1 Polymorphism and Risk of Laryngeal Squamous Cell Carcinoma.