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SNP information rs11200638

RS11200638

Normal allele: GG

Polymorphism rs11200638 is related to topics like this:

Smoking genes

Every year, tobacco smoking causes the demise of five million individuals worldwide and heightens...

Research and publications:

  17053108   HTRA1 promoter polymorphism in wet age-related macular degeneration.

  17053109   A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.

  17327825   An update on the genetics of age-related macular degeneration.

  17426452   HTRA1 variant confers similar risks to geographic atrophy and neovascular age-related macular degeneration.

  17438519   HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.

  17568988   Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.

  17692272   LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population.

  17884985   A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.

  17904186   HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population.

  17917691   Genetic markers and biomarkers for age-related macular degeneration.

  18079691   PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population.

  18162041   Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.

  18164066   Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.

  18206206   Association of HTRA1 polymorphism and bilaterality in advanced age-related macular degeneration.

  18207215   Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with age-related macular degeneration.

  18301036   HTRA1 polymorphism in dry and wet age-related macular degeneration.

  18316707   HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH.

  18362109   Genotype-phenotype correlations for exudative age-related macular degeneration associated with homozygous HTRA1 and CFH genotypes.

  18427598   Human HtrA1 in the archived eyes with age-related macular degeneration.

  18436811   Variants in the 10q26 gene cluster (LOC387715 and HTRA1) exhibit enhanced risk of age-related macular degeneration along with CFH in Indian patients.

  18511946   Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA.

  18515590   Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy.

  18535016   Rhesus monkeys and humans share common susceptibility genes for age-related macular disease.

  18682806   Joint effects of polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH genes on AMD in a Caucasian population.

  18682812   Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.

  18718667   The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.

  18939352   Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population.

  19026638   Meta-analysis of the association of the HTRA1 polymorphisms with the risk of age-related macular degeneration.

  19026761   Molecular pathology of age-related macular degeneration.

  19048105   Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.

  19065273   Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel.

  19169232   Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.

  19187590   Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population.

  19202148   Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.

  19255159   Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria.

  19259132   Multilocus analysis of age-related macular degeneration.

  19491722   Analyses of single nucleotide polymorphisms and haplotype linkage of LOC387715 and the HTRA1 gene in exudative age-related macular degeneration in a Chinese cohort.

  19628747   Toll-like receptor polymorphisms and age-related macular degeneration: replication in three case-control samples.

  19680273   ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population.

  19786043   Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach.

  19796758   Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.

  19798546   Association of HTRA1 promoter polymorphism with spinal disc degeneration in Japanese women.

  19845562   Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients.

  19933179   Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms.

  19933189   Compound heterozygosity of two novel truncation mutations in RP1 causing autosomal recessive retinitis pigmentosa.

  19933195   Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10, region q26.

  20090210   Mediators of ocular angiogenesis.

  20132989   Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population.

  20140183   Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration.

  20157352   Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population.

  20161815   SERPING1 polymorphisms in polypoidal choroidal vasculopathy.

  20207970   Identification of novel substrates for the serine protease HTRA1 in the human RPE secretome.

  20381870   Progression of geographic atrophy and genotype in age-related macular degeneration

  20445115   An intergenic region between the tagSNP rs3793917 and rs11200638 in the HTRA1 gene indicates association with age-related macular degeneration.

  20456446   LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.

  20664794   Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina.

  20678803   Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration.

  20689796   Monozygotic twins with polypoidal choroidal vasuculopathy.

  20881291   Persons with age-related maculopathy risk genotypes and clinically normal eyes have reduced mesopic vision.

  21031019   LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis.

  21045241   Age-related macular degeneration: genetic and environmental factors of disease.

  21067572   Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy.

  21122828   ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.

  21151600   Involvement of genetic factors in the response to a variable-dosing ranibizumab treatment regimen for age-related macular degeneration.

  21191724   Haplotype analysis of the ARMS2/HTRA1 region in Japanese patients with typical neovascular age-related macular degeneration or polypoidal choroidal vasculopathy.

  21203342   Elevated C-reactive protein levels and ARMS2/HTRA1 gene variants in subjects without age-related macular degeneration.

  21252205   Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency.

  21402993   Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.

  21558292   CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration.

  21609220   Genetics of age-related macular degeneration: current concepts, future directions.

  21609242   Age-related macular degeneration-susceptibility single nucleotide polymorphisms in a han chinese control population.

  21654887   Age-related macular degeneration.

  21684273   Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy.

  21811649   CFH, VEGF, and PEDF genotypes and the response to intravitreous injection of bevacizumab for the treatment of age-related macular degeneration.

  21878851   Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration.

  21887094   Update on the role of genetics in the onset of age-related macular degeneration.

  22046503   Pharmacogenetics and age-related macular degeneration.

  22155603   Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.

  22253485   The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis).

  22259222   Chlamydia infection status, genotype, and age-related macular degeneration.

  22275803   The association of CD36 variants with polypoidal choroidal vasculopathy compared to typical neovascular age-related macular degeneration.

  22293892   A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland - a brief report.

  22324898   Genetics of immunological and inflammatory components in age-related macular degeneration.

  22491416   Differentiation of exudative age-related macular degeneration and polypoidal choroidal vasculopathy in the ARMS2/HTRA1 locus.

  22503691   How does the macula protect itself from oxidative stress?

  22509112   Genetic associations in polypoidal choroidal vasculopathy: a systematic review and meta-analysis.

  22536038   Major single nucleotide polymorphisms in polypoidal choroidal vasculopathy: a comparative analysis between Thai and other Asian populations.

  22556410   Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.

  22558131   Comprehensive analysis of Copy Number Variation of genes at chromosome 1 and 10 loci associated with late age related macular degeneration.

  22618592   Association of genetic polymorphisms and age-related macular degeneration in Chinese population.

  22666427   Modelling the genetic risk in age-related macular degeneration.

  22699975   Genetic analysis of simultaneous geographic atrophy and choroidal neovascularization.

  22815632   COL1A2 polymorphic markers confer an increased risk of neovascular age-related macular degeneration in a Han Chinese population.

  22905135   Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis.

  22933840   Association analysis of genetic and environmental risk factors in the cuticular drusen subtype of age-related macular degeneration.

  23204795   Pharmacogenetic influence of LOC387715/HTRA1 on the efficacy of bevacizumab treatment for age-related macular degeneration in a Korean population.

  23209345   Mechanism of inflammation in age-related macular degeneration.

  23209669   Effect of the Gas6 c.834+7G>A polymorphism and the interaction of known risk factors on AMD pathogenesis in Hungarian patients.

  23213279   Positive association of CD36 gene variants with the visual outcome of photodynamic therapy in polypoidal choroidal vasculopathy.

  23326481   Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy.

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