Normal allele: TT
IL2RA gene polymorphism associated with type 1 diabetes.
Polymorphism rs12722495 is related to topics like this:
Research and publications:
19073967 Shared and distinct genetic variants in type 1 diabetes and celiac disease
19701192 Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.
19956106 Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
20805105 Synthetic associations in the context of genome-wide association scan signals
21179116 An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.
21266329 Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs.
21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
21873553 Genetic analysis of adult-onset autoimmune diabetes.
22770979 Presence of multiple independent effects in risk loci of common complex human diseases.
23804261 From markers to molecular mechanisms: type 1 diabetes in the post-GWAS era.
26106387 Pathogenesis of Systemic Sclerosis.
26133380 Associations of Independent IL2RA Gene Variants with Intermediate Uveitis.
28870212 Chromosome contacts in activated T cells identify autoimmune disease candidate genes.
31808541 Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells.