SNP information rs909253

Research and publications:

  12426569   Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.

  12746914   Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity.

  14681301   Association of tumor necrosis factor polymorphisms with asthma and serum total IgE.

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16839190   Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.

  17018637   Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma

  17174749   Linkage disequilibrium with predisposing DR3 haplotypes accounts for apparent effects of tumor necrosis factor and lymphotoxin-alpha polymorphisms on type 1 diabetes susceptibility

  17216494   Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17450233   Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma

  17517687   Association of variants in the BAT1-NFKBIL1-LTA genomic region with protection against myocardial infarction in Europeans.

  17701899   Flexible design for following up positive findings

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  18423522   Estimating odds ratios in genome scans: an approximate conditional likelihood approach

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18687755   Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population

  18704761   Molecular genetics of myocardial infarction.

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  18811622   Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma

  18990758   Genetic variation in tumor necrosis factor and canonical nuclear factor-kappaB pathway and risk of non-Hodgkin's lymphoma

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19167443   Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia

  19225544   Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19281305   Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19409079   Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  19615068   The role of TNF genetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study

  19654554   The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma

  19700502   Synopsis and synthesis of candidate-gene association studies in chronic lymphocytic leukemia: the CUMAGAS-CLL information system

  20031567   Assessing candidate inflammatory and thrombotic genes for venous thromboembolism risk: the Women's Genome Health Study.

  20047977   Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium

  20049212   Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS).

  20112337   Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers

  20357209   Molecular genetic studies of gene identification for osteoporosis: the 2009 update

  20418110   Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer

  20459604   Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes.

  20461113   A screening methodology based on Random Forests to improve the detection of gene-gene interactions.

  20650817   Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes.

  20734064   A large-scale candidate gene association study of age at menarche and age at natural menopause.

  20878356   Role of ethnic variations in TNF-α and TNF-β polymorphisms and risk of breast cancer in India.

  21029472   A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults.

  21149504   Common variations in genes encoding C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 and risk of clinical diabetes in the Women's Health Initiative observational study.

  21315679   Green tea consumption, inflammation and the risk of primary hepatocellular carcinoma in a Chinese population

  21407237   Variants in the inflammatory IL6 and MPO genes modulate stroke susceptibility through main effects and gene-gene interactions.

  21658613   Host genetics in follicular lymphoma.

  21686124   Design and validity of a clinic-based case-control study on the molecular epidemiology of lymphoma.

  21791631   Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

  21867552   Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites.

  21960067   Current concepts and future directions in the pathogenesis and treatment of non-infectious intraocular inflammation.

  21985478   TNFA-863 polymorphism is associated with a reduced risk of chronic obstructive pulmonary disease: a replication study.

  22001640   Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysis.

  22190997   Characterization of Single-Nucleotide Polymorphisms in the Tumor Necrosis Factor α Promoter Region and in Lymphotoxin α in Squamous Intraepithelial Lesions, Precursors of Cervical Cancer.

  22248077   ESR1, HK3 and BRSK1 gene variants are associated with both age at natural menopause and premature ovarian failure.

  22294627   Association between genetic variants at the tumor necrosis factor/lymphotoxin β/lymphotoxin β locus and primary Sjögren's syndrome in Scandinavian samples.

  22615793   Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.

  22666399   Tumor necrosis factor β-induced protein 8 polymorphism and the risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.

  22748850   A functional polymorphism of lymphotoxin-alpha (LTA) gene rs909253 is associated with gastric cancer risk in an Asian population.

  22749237   Tumor necrosis factor -308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients.

  22769019   Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population.

  22882567   The +252A/G polymorphism in the lymphotoxin-α gene increases the risk of asthma: a meta-analysis.

  22957039   Candidate polymorphisms and severe malaria in a Malian population.

  23029405   Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.

  23029430   Prognostic role of host cyclooxygenase and cytokine genotypes in a Caucasian cohort of patients with gastric adenocarcinoma.

  23071570   Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level.

  23086128   Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer.

  23148654   Pandemic influenza A/H1N1 virus infection and TNF, LTA, IL1B, IL6, IL8, and CCL polymorphisms in Mexican population: a case-control study.

  23159874   Pro-inflammatory cytokine gene polymorphisms and threat for coronary heart disease in a North Indian Agrawal population.

  23294973   Association of TNF-α polymorphism rs1800629 with multisomatoform disorder in a group of German patients and healthy controls: an explorative study.

  23316245   The host genetic diversity in malaria infection.

  23360674   Genetic variation may modify ovarian reserve in female childhood cancer survivors.

  23391141   Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab.

  23527081   A large scale gene-centric association study of lung function in newly-hired female cotton textile workers with endotoxin exposure.

  24054031   Genetic variation in cytokine-related genes and migraine susceptibility.

  24136744   Positive association between lymphotoxin-alpha variation rs909253 and cancer risk: a meta-analysis based on 36 case-control studies.

  24566624   Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis.

  24702779   Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia.

  24896147   Role of TNF block genetic variants in HIV-associated sensory neuropathy in black Southern Africans.

  24959879   Effects of tumor necrosis factor-β (TNF-β) 252A>G polymorphism on the development of migraine: a meta-analysis.

  25063351   Tumor necrosis factor beta NcoI polymorphism (rs909253) is associated with inflammatory and metabolic markers in acute ischemic stroke.

  25137520   Heavy metals, organic solvents, and multiple sclerosis: An exploratory look at gene-environment interactions.

  25315199   Genetic association and gene expression studies suggest that genetic variants in the SYNE1 and TNF genes are related to menstrual migraine.

  25383745   HIV-infection, atherosclerosis and the inflammatory pathway: candidate gene study in a Spanish HIV-infected population.

  25962811   Non-Hodgkin Lymphoma, Body Mass Index, and Cytokine Polymorphisms: A Pooled Analysis from the InterLymph Consortium.

  26399644   Immune-Inflammatory and Oxidative and Nitrosative Stress Biomarkers of Depression Symptoms in Subjects with Multiple Sclerosis: Increased Peripheral Inflammation but Less Acute Neuroinflammation.

  26445852   Genetic biomarkers of susceptibility and progression of Barrett's esophagus to dysplasia and cancer: a systematic review and meta-analysis.

  26657940   TNF, IL6, and IL1B Polymorphisms Are Associated with Severe Influenza A (H1N1) Virus Infection in the Mexican Population.

  26658659   Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.

  26659608   A Novel Electrochemical Microfluidic Chip Combined with Multiple Biomarkers for Early Diagnosis of Gastric Cancer.

  26732588   Genetic, Immune-Inflammatory, and Oxidative Stress Biomarkers as Predictors for Disability and Disease Progression in Multiple Sclerosis.

  26861312   Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

  27417569   Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases.

  27419078   Interleukin-18 gene promoter 607A polymorphism, but not 137C polymorphism, is a protective factor for ischemic stroke in the Chinese population: A meta-analysis.

  27536357   Genetic predisposition to Barrett's esophagus: lessons from early research.

  27592234   Variants in LTA, TNF, IL1B and IL10 genes associated with the clinical course of sepsis.

  28256194   Polymorphic Variations Associated With Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients.