SNP information rs680244

Research and publications:

  16314871   Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes.

  17373692   No evidence for association between 19 cholinergic genes and bipolar disorder.

  18163978   The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.

  18414406   Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

  18519524   Variants in nicotinic receptors and risk for nicotine dependence

  18618000   A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction

  19064933   Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

  19436041   Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19628476   Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  20554942   Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

  20700436   Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD

  20808433   Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population

  20854418   CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences

  21079997   Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence

  21168125   TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood

  21268243   Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy

  21949713   Genetics of sputum gene expression in chronic obstructive pulmonary disease.

  22042234   Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.

  22241830   Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

  22290489   Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

  22291610   A flexible Bayesian model for studying gene-environment interaction.

  22382757   The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

  22648373   Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.

  22899653   Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.

  23029550   Associations between variation in CHRNA5-CHRNA3-CHRNB4, body mass index and blood pressure in the Northern Finland Birth Cohort 1966.

  23689675   Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents.

  23943838   Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults.

  24055496   A glimpse into the future - Personalized medicine for smoking cessation.

  24588897   CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  25045619   The Genetics, Neurogenetics and Pharmacogenetics of Addiction.

  25214750   Genomics and personalized medicine: CHRNA5-CHRNA3-CHRNB4 and smoking cessation treatment.

  25233467   Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

  25572450   Response to Transdermal Selegiline Smoking Cessation Therapy and Markers in the 15q24 Chromosomal Region.

  25642160   Nicotinic receptor modulation to treat alcohol and drug dependence.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26010901   Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  31061854   Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment.

  31342675   Impact of CHRNA5 polymorphisms on the risk of schizophrenia in the Chinese Han population.