SNP information rs667282

Research and publications:

  18414406   Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

  18519524   Variants in nicotinic receptors and risk for nicotine dependence

  19330903   Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19491260   Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations.

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  20554942   Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

  20587604   Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans

  21079997   Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence

  21081471   Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study

  21808284   Gender-stratified gene and gene-treatment interactions in smoking cessation.

  22241830   Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

  22832964   Genome-wide meta-analyses of smoking behaviors in African Americans.

  23056235   Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.

  23576140   Is susceptibility locus for lung cancer in the 15q25 nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 associated with risk of gastric cancer?

  23844051   Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

  23942621   Interaction between polygenic risk for cigarette use and environmental exposures in the Detroit Neighborhood Health Study.

  24667010   Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.

  25133033   Epidemiological studies of esophageal cancer in the era of genome-wide association studies.

  26981579   Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.

  27050379   Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer.

  27162544   Combining Telomerase Reverse Transcriptase Genetic Variant rs2736100 with Epidemiologic Factors in the Prediction of Lung Cancer Susceptibility.

  31942417   Chronic Obstructive Pulmonary Disease Risk and Smoking Cessation Changes Induced by CHRNA5-A3 and CHRNB3-A6 Variation in a Chinese Male Population.

  32104210   Inherited lung cancer: a review.