SNP information rs3743078

Research and publications:

  17135278   Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

  18165968   Identification of pharmacogenetic markers in smoking cessation therapy

  18414406   Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

  18519524   Variants in nicotinic receptors and risk for nicotine dependence

  18571741   Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research

  19029397   Nicotinic receptor gene variants influence susceptibility to heavy smoking

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  19859904   Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

  20234319   Association of the CHRNA3 locus with lung cancer risk and prognosis in Chinese Han population.

  20485328   Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

  20631687   Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility

  20886544   Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance

  21191315   Genetic association of bipolar disorder with the β(3) nicotinic receptor subunit gene

  21229299   Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers

  21808284   Gender-stratified gene and gene-treatment interactions in smoking cessation.

  22241830   Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

  22438940   Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.

  24375168   ADHD diagnosis may influence the association between polymorphisms in nicotinic acetylcholine receptor genes and tobacco smoking.

  24588897   CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.

  24667010   Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.