SNP information rs2236196

Research and publications:

  15154117   A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.

  17135278   Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

  17503330   A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence.

  17768273   CHRNA4 and tobacco dependence: from gene regulation to treatment outcome.

  18165968   Identification of pharmacogenetic markers in smoking cessation therapy

  18534558   Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.

  18571741   Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research

  18593715   Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.

  18618000   A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction

  18698231   Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

  19029397   Nicotinic receptor gene variants influence susceptibility to heavy smoking

  19238175   New insights into the genetics of addiction

  19259974   Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

  19290018   Association of nicotinic acetylcholine receptor subunit alpha 4 polymorphisms with nicotine dependence in 5500 Germans.

  19482438   Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  20584212   Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans

  20624154   Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes

  20854418   CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences

  20942817   Pharmacogenetics of new analgesics.

  21079997   Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence

  21445957   Association of CHRNA4 polymorphisms with smoking behavior in two populations.

  22048466   Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.

  22103610   Biomarkers to optimize the treatment of nicotine dependence.

  22180580   Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation.

  22290489   Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

  22309839   Association study of 45 candidate genes in nicotine dependence in Han Chinese.

  23691092   Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  25778907   The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26598068   Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  27827986   Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence.