SNP information rs2036527

Research and publications:

  17373692   No evidence for association between 19 cholinergic genes and bipolar disorder.

  18414406   Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

  18519524   Variants in nicotinic receptors and risk for nicotine dependence

  18759969   In search of causal variants: refining disease association signals using cross-population contrasts

  19029397   Nicotinic receptor gene variants influence susceptibility to heavy smoking

  19247474   Genome-wide and candidate gene association study of cigarette smoking behaviors

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  20554942   Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

  20587604   Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans

  20624154   Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes

  22241830   Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

  22495174   DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers.

  22832964   Genome-wide meta-analyses of smoking behaviors in African Americans.

  22837378   Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

  22945651   Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

  23221128   Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.

  23942621   Interaction between polygenic risk for cigarette use and environmental exposures in the Detroit Neighborhood Health Study.

  24733007   Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  26010901   Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26351737   Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use.

  26948517   Genetic scores of smoking behaviour in a Chinese population.

  26981579   Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  27294413   Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.

  27335628   A prospective and retrospective analysis of smoking behavior changes in ever smokers with high risk for lung cancer from New Mexico and Pennsylvania.

  27393504   Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.

  27694844   Fisher's adaptive combination method for joint analysis of multiple phenotypes in association studies.

  28884473   Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers.

  29621993   Cholinergic receptor nicotinic alpha 5 subunit polymorphisms are associated with smoking cessation success in women.

  29942042   A decade in psychiatric GWAS research.