SNP information rs1317286

Research and publications:

  18227835   Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking

  18571741   Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research

  18759969   In search of causal variants: refining disease association signals using cross-population contrasts

  19259974   Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

  19330903   Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans

  19443489   Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  19859904   Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

  20393456   Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers.

  20548021   Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

  20554942   Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

  20808433   Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population

  21229299   Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers

  21808284   Gender-stratified gene and gene-treatment interactions in smoking cessation.

  22495174   DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers.

  22837378   Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

  23027417   Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor.

  23429840   Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  25051068   Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analyses.

  29879020   Association analysis of CHRNA3 polymorphisms with schizophrenia in a Chinese Han population: A case-control study.

  33324248   Genetic Determinants of Gating Functions: Do We Get Closer to Understanding Schizophrenia Etiopathogenesis?

  34555889   Association Study of Polymorphisms in Neuronal Nicotinic Acetylcholine Receptor Subunit Genes With Schizophrenia in the Han Chinese Population.