SNP information rs1044396

Research and publications:

  15154117   A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.

  17135278   Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

  17503330   A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence.

  17613539   Association of attentional network function with exon 5 variations of the CHRNA4 gene.

  17948872   Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD.

  18534558   Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.

  18571741   Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research

  18618000   A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction

  19211801   Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory.

  19238175   New insights into the genetics of addiction

  19259974   Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

  19290018   Association of nicotinic acetylcholine receptor subunit alpha 4 polymorphisms with nicotine dependence in 5500 Germans.

  19429020   Individual variation in a cholinergic receptor gene modulates attention.

  19482438   Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence

  20631687   Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility

  20736995   Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence

  20942817   Pharmacogenetics of new analgesics.

  21130611   Evidence for the modality independence of the genetic epistasis between the dopaminergic and cholinergic system on working memory capacity.

  21445957   Association of CHRNA4 polymorphisms with smoking behavior in two populations.

  21606948   Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes

  22008229   Association of CHRNA4 polymorphism with depression and loneliness in elderly males.

  22180580   Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation.

  22290489   Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

  22373960   A cognitive phenotype for a polymorphism in the nicotinic receptor gene CHRNA4.

  22722381   The role of the CHRNA4 gene in Internet addiction: a case-control study.

  22760121   Interaction of the cholinergic system and the hypothalamic-pituitary-adrenal axis as a risk factor for depression: evidence from a genetic association study.

  22947540   The dopamine D2 receptor gene DRD2 and the nicotinic acetylcholine receptor gene CHRNA4 interact on striatal gray matter volume: evidence from a genetic imaging study.

  23240931   A novel differential susceptibility gene: CHRNA4 and moderation of the effect of maltreatment on child personality.

  23350800   Nominal association with CHRNA4 variants and nicotine dependence.

  24819610   DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory.

  25639542   Individual response speed is modulated by variants of the gene encoding the alpha 4 sub-unit of the nicotinic acetylcholine receptor (CHRNA4).

  25642160   Nicotinic receptor modulation to treat alcohol and drug dependence.

  25647695   Modulation of nicotine effects on selective attention by DRD2 and CHRNA4 gene polymorphisms.

  25729002   Association of a nicotinic receptor gene polymorphism with spontaneous eyeblink rates.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  25934188   The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26079805   Nicotinergic Modulation of Attention-Related Neural Activity Differentiates Polymorphisms of DRD2 and CHRNA4 Receptor Genes.

  26982087   CHRNA4 was associated with prepulse inhibition of schizophrenia in Chinese: a pilot study.

  27054571   Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample.

  27109789   Cholinergic modulation of auditory P3 event-related potentials as indexed by CHRNA4 and CHRNA7 genotype variation in healthy volunteers.

  27123786   A role for attention during wilderness navigation: Comparing effects of BDNF, KIBRA, and CHRNA4.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  28582665   The influence of CHRNA4, COMT, and maternal sensitivity on orienting and executive attention in 6-month-old infants.

  28877969   Overdominant Effect of a CHRNA4 Polymorphism on Cingulo-Opercular Network Activity and Cognitive Control.

  29240768   The association between the nicotinic acetylcholine receptor α4 subunit gene (CHRNA4) rs1044396 and Internet gaming disorder in Korean male adults.

  31402126   Association Between Nicotine-dependent Gene Polymorphism and Smoking Cessation in Patients With Lung Cancer.

  33096746   Genetic Landscape of Common Epilepsies: Advancing towards Precision in Treatment.

  34555889   Association Study of Polymorphisms in Neuronal Nicotinic Acetylcholine Receptor Subunit Genes With Schizophrenia in the Han Chinese Population.

  35222535   Comparative Assessment of Outcomes in Drug Treatment for Smoking Cessation and Role of Genetic Polymorphisms of Human Nicotinic Acetylcholine Receptor Subunits.

  23757202   Free the data: one laboratory's approach to knowledge-based classification of genomic variants and preparation for integration of genomic data into EMR.

  20493238   CHRNA4 genetic variation does not modulate attention in Parkinson's disease.