Normal allele: CC
A SNP variant in ErbB4 is associated with bipolar affective disorder, major depressive disorder and schizophrenia.
Polymorphism rs839523 is related to topics like this:
Research and publications:
17164265 Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia.
17598910 Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.
18478032 Neuregulin 1 in neural development, synaptic plasticity and schizophrenia.
19197363 A genome-wide investigation of SNPs and CNVs in schizophrenia.
19932755 Imaging genetics of structural brain connectivity and neural integrity markers.
20886074 Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain.
20934307 The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions.
21832192 Genetic association of ErbB4 and human cortical GABA levels in vivo.
21993442 Analysis of association between common SNPs in ErbB4 and bipolar affective disorder, major depressive disorder and schizophrenia in the Han Chinese population.
22115776 Schizophrenia candidate gene ERBB4: covert routes of vulnerability to psychosis detected at the population level.
22416237 The effects of psychosis risk variants on brain connectivity: a review.
26877878 The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.
27895608 Genetic Consideration of Schizotypal Traits: A Review.
28225484 Association between ErbB4 single nucleotide polymorphisms and susceptibility to schizophrenia: A meta-analysis of case-control studies.
28394697 Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia.
28425244 Genetic association analysis of ERBB4 polymorphisms with the risk ofschizophrenia susceptibility in a Jordanian population of Arab descent.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.