SNP information rs401681

Research and publications:

  18978787   Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

  18978790   Lung cancer susceptibility locus at 5p15.33.

  19151717   Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

  19423719   Update in lung cancer 2008.

  19465454   The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung

  19578363   New common variants affecting susceptibility to basal cell carcinoma.

  19654303   Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

  19767754   Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility.

  19774073   Genetic epidemiology of glioblastoma multiforme: confirmatory and new findings from analyses of human leukocyte antigen alleles and motifs.

  19812545   Origins and functional impact of copy number variation in the human genome.

  19836008   A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.

  19903803   Re: Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.

  19916168   Genome-wide association studies--a summary for the clinical gastroenterologist.

  20022891   The evolving discipline of molecular epidemiology of cancer

  20101243   A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.

  20142248   Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.

  20445798   Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20543847   Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.

  20546537   Genome-wide association studies of pigmentation and skin cancer: a review and meta-analysis.

  20548021   Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

  20549820   Telomere length and genetic analyses in population-based studies of endometrial cancer risk.

  20570912   No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk.

  20585100   Genome-wide association studies of cancer.

  20587082   ABO blood group and other genetic variants associated with pancreatic cancer.

  20597107   The association of telomere length and genetic variation in telomere biology genes.

  20628624   Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".

  20802237   Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck.

  20860009   Prostate cancer risk alleles significantly improve disease detection and are associated with aggressive features in patients with a "normal" prostate specific antigen and digital rectal examination.

  20972438   A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

  21081471   Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study

  21116649   Genetic variants in telomere-maintaining genes and skin cancer risk.

  21160077   Genetic correction of PSA values using sequence variants associated with PSA levels.

  21219822   [Recent progress in genetic variants associated with cancer and their implications in diagnostics development].

  21332924   Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme.

  21367958   Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality.

  21498636   Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus.

  21708826   TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres.

  21743467   Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.

  21750109   European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

  21771723   Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.

  21820706   Prostate cancer risk alleles and their associations with other malignancies.

  21849791   Including additional controls from public databases improves the power of a genome-wide association study.

  21927616   Genetic susceptibility to bladder cancer risk and outcome.

  21966413   Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population.

  21983787   Genome-wide association study identifies three new melanoma susceptibility loci.

  21993562   Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk.

  21994403   Telomere length and TERT functional polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck.

  22077888   Association of prostate cancer risk alleles with unfavourable pathological characteristics in potential candidates for active surveillance.

  22101116   Evaluation of multiple risk-associated single nucleotide polymorphisms versus prostate-specific antigen at baseline to predict prostate cancer in unscreened men.

  22119407   Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.

  22125638   Pancreatic cancer susceptibility loci and their role in survival.

  22134622   Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.

  22221621   The TERT rs2736100 polymorphism and cancer risk: a meta-analysis based on 25 case-control studies.

  22370939   Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.

  22404340   Replication of results of genome-wide association studies on lung cancer susceptibility loci in a Korean population.

  22510351   Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.

  22586632   Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke.

  22662130   Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method.

  22675468   Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus.

  22893025   Association between TERT-CLPTM1L rs401681[C] allele and NMSC cancer risk: a meta-analysis including 45,184 subjects.

  22899653   Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.

  22970196   Genetic variation in telomere maintenance genes, telomere length and breast cancer risk.

  23028716   Association test based on SNP set: logistic kernel machine based test vs. principal component analysis.

  23050049   Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study.

  23152778   Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.

  23180869   Genome-wide association study of survival in patients with pancreatic adenocarcinoma.

  23221128   Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.

  23349013   Genetic susceptibility to lung cancer--light at the end of the tunnel?

  23433592   Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer--a case-control study in a Chinese population.

  23535824   Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

  23707794   Genetic variants in TERT-CLPTM1L genetic region associated with several types of cancer: a meta-analysis.

  23900074   A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.

  24274136   Biobanking across the phenome - at the center of chronic disease research.

  24491308   Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men.

  24577890   Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population.

  24615522   Quantitative assessment of common genetic variants on chromosome 5p15 and lung cancer risk.

  24615621   Multigene pathway-based analyses identify nasopharyngeal carcinoma risk associations for cumulative adverse effects of TERT-CLPTM1L and DNA double-strand breaks repair.

  24642353   Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk.

  24861918   Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population.

  24907075   Association between CLPTM1L polymorphisms (rs402710 and rs401681) and lung cancer susceptibility: evidence from 27 case-control studies.

  24957041   CRR9p polymorphism as a protective factor for lung cancer.

  25007268   TERT-CLPTM1L Rs401681 C>T polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population.

  25077817   Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.

  25159867   Common variants modify the age of onset for basal cell carcinomas in Gorlin syndrome.

  25233467   Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

  25284078   Association between CLPTM1L-TERT rs401681 polymorphism and risk of pancreatic cancer: a meta-analysis.

  25347272   Genetic variations rs11892031 and rs401681 are associated with bladder cancer risk in a Chinese population.

  25415319   Association of GWAS-identified lung cancer susceptibility loci with survival length in patients with small-cell lung cancer treated with platinum-based chemotherapy.

  25457634   Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.

  25560306   Known susceptibility SNPs for sporadic prostate cancer show a similar association with "hereditary" prostate cancer.

  25658847   Do variants associated with susceptibility to pancreatic cancer and type 2 diabetes reciprocally affect risk?

  25837821   Inherited genetic variants associated with occurrence of multiple primary melanoma.

  25940397   TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.

  26304507   Association of gastrointestinal gland cancer susceptibility loci with esophageal carcinoma among the Chinese Han population: a case-control study.

  26590902   Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci.

  26621837   Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.

  26672516   Association between MDM2 SNP309 T>G polymorphism and the risk of bladder cancer: new data in a Chinese population and an updated meta-analysis.