Normal allele: AA
The CD58 genetic variant is associated with risk of multiple sclerosis and rheumatoid arthritis.
Polymorphism rs2300747 is related to topics like this:
Research and publications:
19237575 The role of the CD58 locus in multiple sclerosis.
19525953 Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
19865102 Multiple sclerosis susceptibility alleles in African Americans.
19898481 Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
20182566 The genetic aspects of multiple sclerosis.
20186855 What role for genetics in the prediction of multiple sclerosis?
20362272 Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come.
20405052 The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.
21247752 Revealing the genetic basis of multiple sclerosis: are we there yet?
21280076 Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.
22190364 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
23326239 A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
23730204 Progress in multiple sclerosis genetics.
27331013 Association of EVI5 rs11808092, CD58 rs2300747, and CIITA rs3087456 polymorphisms with multiple sclerosis risk: A meta-analysis.
27386562 Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
28601281 Association of CD58 gene polymorphisms with NMO spectrum disorders in a Han Chinese population.
30128676 High-resolution melting curve analysis of polymorphisms within CD58, CD226, HLA-G genes and association with multiple sclerosis susceptibility in a subset of Iranian population: a case-control study.
30643196 POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.
31505972 Association of CD58 Polymorphisms and its Protein Expression with the Development and Prognosis of Autoimmune Thyroid Diseases.
32257069 Association of CD58 polymorphism and multiple sclerosis in Malaysia: a pilot study.